encyclopedia of medical concepts
ψ 

Oxazolidinones

More information in Books or onNLM PubMed
Definition: Derivatives of oxazolidin-2-one. They represent an important class of synthetic antibiotic agents.     
Pharmacological Action Anti-Infective Agents; Protein Synthesis Inhibitors
Examples Cycloserine; Furazolidone; Nifuratel 		Other names Oxazolidin 2 one; 2 oxazolidinone; 2 Oxazolidone; 1,3 Oxazolidine 2 one; 1,3 Oxazolidin 2 one; 2-oxazolidinone; 1,3-Oxazolidine-2-one; 2-Oxazolidone; Oxazolidin-2-one; 1,3-Oxazolidin-2-one
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-phenyl-4-bis(methylthio)methyleneoxazol-5-one  0   *Oxazolidinones. Org Biomol Chem. 2011 Aug 21;9(16):5793-801
parnafungin A2  0   *Oxazolidinones. J Org Chem. 2010 Dec 3;75(23):8224-33
parnafungin A1  0   *Oxazolidinones. J Org Chem. 2010 Dec 3;75(23):8224-33
synoxazolidinone B  0   *Oxazolidinones Guanidine/*analogs & derivatives. Org Lett. 2010 Nov 5;12(21):4752-5
synoxazolidinone A  0   *Oxazolidinones Guanidine/*analogs & derivatives. Org Lett. 2010 Nov 5;12(21):4752-5
N-((3-(4-(1,1-dioxidothiomorpholin-4-yl)-3,5-difluorophenyl)-2-oxo-1,3-oxazolidin-5-yl)methyl)acetamide  0   *Cyclic S-Oxides *Oxazolidinones. J Pharmacol Exp Ther 2010 Sep 1;334(3):936-44
N-((3-(2-fluoro-4'-(((1H-1,2,3-triazol-5-ylmethyl)amino)methyl)(1,1'-biphenyl)-4-yl)-2-oxo-5-oxazolidinyl)methyl)acetamide  0   *Oxazolidinones. Antimicrob Agents Chemother 2010 Jun;54(6):2540-8
agelastatin F  0   *Alkaloids *Oxazolidinones. J Nat Prod. 2010 Apr 23;73(4):720-3
agelastatin E  0   *Alkaloids *Oxazolidinones. J Nat Prod. 2010 Apr 23;73(4):720-3
4-oxo-4-(2-oxooxazolidin-3-yl)but-2-enoic acid ethyl ester  0   *Fumarates *Oxazolidinones. Int Immunopharmacol 2010 Feb;10(2):163-8
3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-hydroxymethyloxazolidin-2-one  0   *Tetrazoles *Oxazolidinones. Antimicrob Agents Chemother 2008 Dec;52(12):4442-7
OCID0050  0   *Oxazolidinones. J Antimicrob Chemother. 2009 Oct;64(4):797-800
PNU-100480  0   *Oxazolidinones Tuberculosis, Pulmonary/drug therapy. Am J Respir Crit Care Med. 2009 Aug 15;180(4):371-6
5-(2-pyrrolidinyl)oxazolidinone  0   *Pyrrolidines *Oxazolidinones. Bioorg Med Chem Lett 2009 Feb 1;19(3):854-9
parnafungin D  0   *Oxazolidinones. Bioorg Med Chem Lett 2009 Feb 15;19(4):1224-7
parnafungin C  0   *Oxazolidinones. Bioorg Med Chem Lett 2009 Feb 15;19(4):1224-7
5-ketoclomazone  0   *Isoxazoles *Oxazolidinones. Pest Manag Sci 2008 Oct;64(10):1031-9
2-N-acetyl-2N,3O-oxazolidinone  0   *Oxazolidinones. J Org Chem. 2008 Sep 19;73(18):7181-8
anacetrapib  0   *Oxazolidinones Cholesterol Ester Transfer Proteins/antagonists & inhibitors. Lancet 2007 Dec 8;370(9603):1907-14
3-oxo-1,1-diphenyltetrahydrooxazolo(3,4-a)pyrazine-7-carboxylic acid 4-fluorobenzylamide  0   *Pyrazines *Oxazolidinones Receptors, Neuropeptide/antagonists & inhibitors. J Pharmacol Exp Ther 2008 Jun;325(3):893-901
locostatin  0   *Oxazolidinones. Chem Biol 2005 Sep;12(9):953-4
4,6-di-O-acetyl-N-acetyloxazolidinone  0   *Oxazolidinones. Chem Commun (Camb). 2008 Feb 7;(5):597-9
3-(3-fluoro-4-(1-oxotetrahydrothiopyran-4-yl)phenyl)-2-oxooxazolidine-5-carboxylic acid amide  0   *Cyclic S-Oxides *Oxazolidinones. J Med Chem 2007 Nov 29;50(24):5886-9
lipoxazolidinone C  0   *Oxazolidinones. J Nat Prod 2007 Sep;70(9):1454-7
lipoxazolidinone B  0   *Oxazolidinones. J Nat Prod 2007 Sep;70(9):1454-7
lipoxazolidinone A  0   *Oxazolidinones. J Nat Prod 2007 Sep;70(9):1454-7
AM-7359  0   *Oxazolidinones. J Chemother 2007 Jun;19(3):249-55
N-triphenylmethyl-5-oxazolidinone  0   *Trityl Compounds *Oxazolidinones. J Am Chem Soc 2006 Jul 5;128(26):8581-9
RWJ-416457  0   *Oxazolidinones. Antimicrob Agents Chemother 2007 Jan;51(1):361-5
YC-20 compound  0   *Oxazolidinones. J Antimicrob Chemother 2006 Aug;58(2):452-4
ZTR-5 compound  0   *Tryptamines *Oxazolidinones. J Pharm Biomed Anal 2005 Sep 15;39(3-4):796-800
N-vinyl-2-oxazolidinone  0   *Oxazolidinones. Org Biomol Chem. 2005 Sep 7;3(17):3207-12
RBX 8700  0   *Oxazolidinones. Int J Antimicrob Agents 2005 Jun;25(6):464-8
3-amino-5-morpholinomethyl-2-oxazolidinone  0   *Morpholines *Oxazolidinones. Food Addit Contam 2005 May;22(5):406-14
N-(3-(4H,6H-5-oxa-10b-aza-benzo(e)azulen-8-yl)-2-oxo-oxazolidin-5(S)-ylmethyl)acetamide  0   *Acetamides *Oxazolidinones *Azulenes. Arzneimittelforschung. 2005;55(4):239-44
3-benzyl-4-formyl-5-vinyl-2-oxazolidinone  0   *Oxazolidinones. J Org Chem 2003 Aug 8;68(16):6268-73
DA-7867  0   *Oxazolidinones. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Sep 5;794(2):397-403
PH 027  0   *Triazoles *Oxazolidinones. J Chemother 2003 Apr;15(2):113-7
3-(2-propenoyl)-1,3-oxazolidin-2-one  0   *Oxazolidinones. Chem Pharm Bull (Tokyo) 2002 Sep;50(9):1255-7
XA043 antibiotic  0   *Oxazolidinones. J Mol Biol 2002 Sep 13;322(2):273-9
agelastatin A  0   *Alkaloids *Oxazolidinones. J Am Chem Soc 2002 Aug 7;124(31):9060-1
agelastatin B  0   *Alkaloids *Oxazolidinones. J Am Chem Soc 2002 Aug 7;124(31):9060-1
AZD2563  0   *Oxazolidinones. Diagn Microbiol Infect Dis 2002 Feb;42(2):119-22
4-benzyl-3-benzyloxyacetyl-2-oxazolidinone  0   *Oxazolidinones. Org Lett 1999 Dec 16;1(12):2029-32
NC 1800  0   *Morpholines *Oxazolidinones. Eur J Pharmacol 1997 Jul 30:332(1):89-95
T 794  0   *Naphthalenes *Oxazolidinones. Biol Pharm Bull 1997 Apr;20(4):349-53
terizidone  25683-71-0   *Isoxazoles *Oxazolidinones.
4-isopropyl-3-propionyl-2-oxazolidinone  165657-81-8   *Oxazolidinones. Chem Pharm Bull (Tokyo) 1995 Nov;43(11):1897-901
U 100592  0   *Acetamides *Oxazolidinones.
Pharma Action Anti-Infective Agents 		J Med Chem 1996 Feb 2;39(3):673-9
linezolid  165800-03-3   *Acetamides *Oxazolidinones RNA, Ribosomal, 23S.
Pharma Action Anti-Infective Agents ; Protein Synthesis Inhibitors 		J Med Chem 1996 Feb 2;39(3):673-9ZYVOX; LINEZOLID
clomazone  81777-89-1   *Isoxazoles *Oxazolidinones. Bull environ Contam Toxicol 1995 Jun;54(6):848-54
3-dodecanoyl-4-phosphatidylcholinohydroxymethyl-2-oxazolidinone  153531-48-7   *Organophosphorus Compounds *Oxazolidinones Phospholipases A/antagonists & inhibitors. J Biochem (Tokyo) 1995 Jan;117(1):176-82
CP 92768-2  0   *Benzofurans *Oxazolidinones. Endocrinology 1995 Apr;136(4):1450-8
ER 4539  0   *Oxazolidinones *Benzothiazoles. Xenobiotica 1994 Aug;24(8):819-26
E 2011  0   *Oxazolidinones *Benzothiazoles Stereoisomerism. Xenobiotica 1994 Aug;24(8):819-26
AS 8  0   *Morpholines *Oxazolidinones. Pol J Pharmacol 1994 Jan-Apr;46(1-2):15-20
zolmitriptan  139264-17-8   *Tryptamines *Oxazolidinones.
Pharma Action Serotonin 5-HT1 Receptor Agonists 		Headache 1994 Jul-Aug;34(7):394-9ZOMIG; ZOMIG-ZMT; ZOLMITRIPTAN
N-chloroethyl-1,3-oxazolidin-2-one  2508-01-2   *Oxazolidinones. Biol Mass Spectrom 1994 Mar;23(3):149-58
4-methyl-5-phenyl-1,3-oxazolidin-2-one  77943-39-6   *Oxazolidinones. Acta Crystallogr C 1993 Jun 15;49(Pt 6):1238-40
4-benzyl-3-crotonyl-2-oxazolidinone  133812-16-5   *Benzyl Compounds *Oxazolidinones. Acta Crystallogr C 1992 Sep 15;48(Pt 9):1622-4
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy