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LIM Domain Proteins

More information in Books or onNLM PubMed
Definition: A large class of structurally-related proteins that contain one or more LIM zinc finger domains. Many of the proteins in this class are involved in intracellular signaling processes and mediate their effects via LIM domain protein-protein interactions. The name LIM is derived from the first three proteins in which the motif was found: LIN-11, Isl1 and Mec-3.     
Examples Lim Kinases; LIM-Homeodomain Proteins; Paxillin; Zyxin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Zasp52 protein, Drosophila  0   *Drosophila Proteins *LIM Domain Proteins. Gene Expr Patterns. 2011 Dec;11(8):484-90
LMO4 protein, Xenopus  0   *Xenopus Proteins *LIM Domain Proteins. Dev Biol. 2012 Jan 15;361(2); 313-25
ajuba protein, Drosophila  0   *Drosophila Proteins *LIM Domain Proteins. J Cell Sci 2011 Apr 1;124(Pt 7):1156-66
Prickle1a protein, zebrafish  0   *Zebrafish Proteins *Adaptor Proteins, Signal Transducing *LIM Domain Proteins.
CSRP1 protein, human  0   *Nuclear Proteins *LIM Domain Proteins.
LIM mineralization protein-3, human  0   *Intracellular Signaling Peptides and Proteins *LIM Domain Proteins. Gene Expr. 2010;15(1):27-42
Ablim1 protein, mouse  0   *Microfilament Proteins *LIM Domain Proteins. BMC Dev Biol. 2010;10() (dup#35):54
Lmcd1 protein, rat  0   *Co-Repressor Proteins *LIM Domain Proteins. Blood Press. 2010 Feb;19(1):54-63
Crip2 protein, rat  0   *LIM Domain Proteins. Biochemistry (Mosc) 2009 Mar;74(3):336-41
lmo7a protein, zebrafish  0   *Transcription Factors *Zebrafish Proteins *LIM Domain Proteins. Dev Dyn 2008 Dec;237(12):3940-52
DA1 protein, Arabidopsis  0   *Arabidopsis Proteins *LIM Domain Proteins. Genes Dev 2008 May 15;22(10):1331-6
CRIP2 protein, zebrafish  0   *Zebrafish Proteins *LIM Domain Proteins. Circ Res 2008 Apr 11;102(7):831-9
Lim-8 protein, C elegans  0   *Carrier Proteins *Caenorhabditis elegans Proteins *LIM Domain Proteins. Mol Biol Cell 2007 Nov;18(11):4317-26
Lim-9 protein, C elegans  0   *Carrier Proteins *Caenorhabditis elegans Proteins *LIM Domain Proteins. Mol Biol Cell 2007 Nov;18(11):4317-26
Prickle1b protein, zebrafish  0   *Zebrafish Proteins *Adaptor Proteins, Signal Transducing *LIM Domain Proteins. Dev Biol 2007 Sep 15;309(2):358-72
Prickle1 protein, mouse  0   *Adaptor Proteins, Signal Transducing *LIM Domain Proteins. Int J Mol Med 2003 Feb;11(2):249-56
Ablim3 protein, mouse  0   *Microfilament Proteins *LIM Domain Proteins. J Biol Chem 2007 Mar 16;282(11):8393-403
Ablim2 protein, mouse  0   *Microfilament Proteins *LIM Domain Proteins. J Biol Chem 2007 Mar 16;282(11):8393-403
Prickle2 protein, mouse  0   *Membrane Proteins *LIM Domain Proteins. J Neurosci 2007 Mar 21;27(12):3139-47
Fhl1 protein, rat  0   *Muscle Proteins *LIM Domain Proteins. Life Sci 2007 Jan 9;80(5):460-7
PRICKLE1 protein, human  0   *Tumor Suppressor Proteins *LIM Domain Proteins. Gastroenterology 2006 Oct;131(4):1218-27
Lmo2 protein, mouse  0   *Adaptor Proteins, Signal Transducing *LIM Domain Proteins.
lmo2 protein, zebrafish  0   *Transcription Factors *Zebrafish Proteins *LIM Domain Proteins.
Lmo1 protein, mouse  0   *Nuclear Proteins *Transcription Factors *LIM Domain Proteins.
PDLIM5 protein, human  0   *Adaptor Proteins, Signal Transducing *LIM Domain Proteins. Neurosci Lett 2006 Jun 12;400(3):203-7
PDLIM1 protein, human  0   *Microfilament Proteins *LIM Domain Proteins. J Cell Biochem 1999 Feb 1;72(2):279-85
Prickle protein, Xenopus  0   *DNA-Binding Proteins *Xenopus Proteins *LIM Domain Proteins. Mech Dev 2002 Aug;116(1-2):183-6
Limd1protein, mouse  0   *Intracellular Signaling Peptides and Proteins *LIM Domain Proteins.
ALP-1 protein, C elegans  0   *Caenorhabditis elegans Proteins *Adaptor Proteins, Signal Transducing *LIM Domain Proteins. Dev Dyn 2006 Feb;235(2):530-8
Pdlim2 protein, mouse  0   *Adaptor Proteins, Signal Transducing *LIM Domain Proteins. Immunity 2005 Jun;22(6):729-36
Crip2 protein, mouse  0   *Carrier Proteins *LIM Domain Proteins. Circulation 2005 Sep 13;112(11):1601-11
Mllt4 protein, rat  0   *Microfilament Proteins *LIM Domain Proteins. J Cell Biol 1997 Oct 20;139(2)517-28
Fhl5 protein, mouse  0   *Transcription Factors *LIM Domain Proteins.
FHL5 protein, human  0   *Transcription Factors *LIM Domain Proteins.
PDLIM2 protein, human  0   *Microfilament Proteins *LIM Domain Proteins. Mol Biol Cell 2005 Apr;16(4):1811-22
LMO3 protein, human  0   *Adaptor Proteins, Signal Transducing *LIM Domain Proteins. Cancer Res 2005 Jun 1;65(11):4587-97
Fhl3 protein, mouse  0   *Intracellular Signaling Peptides and Proteins *LIM Domain Proteins.
PRICKLE4 protein, human  0   *Nuclear Proteins *Adaptor Proteins, Signal Transducing *LIM Domain Proteins. Int J Mol Med 2005 Mar;15(3):513-8
XIRP2 protein, human  0   *DNA-Binding Proteins *Nuclear Proteins *LIM Domain Proteins. J Cell Sci. 2004 Oct 15;117(Pt 22):5257-68
XIRP2 protein, mouse  0   *DNA-Binding Proteins *Nuclear Proteins *LIM Domain Proteins. J Cell Sci. 2004 Oct 15;117(Pt 22):5257-68
Lmo4 protein, mouse  0   *Adaptor Proteins, Signal Transducing *LIM Domain Proteins.
Lpp protein, mouse  0   *Cytoskeletal Proteins *LIM Domain Proteins.
Lasp1 protein, mouse  0   *Cytoskeletal Proteins *Homeodomain Proteins *LIM Domain Proteins.
Tgfb1i1 protein, rat  0   *Cytoskeletal Proteins *DNA-Binding Proteins *LIM Domain Proteins.
TGFB1I1 protein, human  0   *Intracellular Signaling Peptides and Proteins *LIM Domain Proteins.
LIMS2 protein, human  0   *Membrane Proteins *Adaptor Proteins, Signal Transducing *LIM Domain Proteins.
Lims2 protein, mouse  0   *Membrane Proteins *Adaptor Proteins, Signal Transducing *LIM Domain Proteins.
Lims1 protein, mouse  0   *Membrane Proteins *Adaptor Proteins, Signal Transducing *LIM Domain Proteins.
Crip1 protein, mouse  0   *Carrier Proteins *LIM Domain Proteins.
Fblim1 protein, mouse  0   *Cytoskeletal Proteins *LIM Domain Proteins. J Cell Biol 2004 Feb 2;164(3):395-405
Nebl protein, mouse  0   *Cytoskeletal Proteins *LIM Domain Proteins. J Biol Chem 2004 May 7;279(19):20401-10
NEBL protein, human  0   *Carrier Proteins *Cytoskeletal Proteins *LIM Domain Proteins. J Biol Chem 2004 May 7;279(19):20401-10
ldb1a protein, zebrafish  0   *DNA-Binding Proteins *Zebrafish Proteins *LIM Domain Proteins.
LDB1 protein, human  0   *DNA-Binding Proteins *Transcription Factors *LIM Domain Proteins.
Fhl1 protein, mouse  0   *Muscle Proteins *Intracellular Signaling Peptides and Proteins *LIM Domain Proteins.
Pdlim4 protein, mouse  0   *Microfilament Proteins *LIM Domain Proteins.
PDLIM4 protein, human  0   *DNA-Binding Proteins *LIM Domain Proteins.
CRIP1 protein, human  0   *Carrier Proteins *LIM Domain Proteins.
Csrp1 protein, mouse  0   *Nuclear Proteins *LIM Domain Proteins.
CRIP2 protein, human  0   *Adaptor Proteins, Signal Transducing *LIM Domain Proteins.
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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