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Lim Kinases

More information in Books or onNLM PubMed
Definition: Serine protein kinases involved in the regulation of ACTIN polymerization and MICROTUBULE disassembly. Their activity is regulated by phosphorylation of a threonine residue within the activation loop by intracellular signaling kinases such as P21-ACTIVATED KINASES and by RHO KINASE.      Other names LIM Motif Containing Protein Kinases; Kinases, Lim; Kinase, LIM; LIM-Kinase; LIM Motif-Containing Protein Kinases; LIM Kinase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Limk1 protein, rat  EC 2.7.11.1   *Lim Kinases.
Limk1 protein, mouse  EC 2.7.11.1   *Lim Kinases.
LIMK1 protein, human  EC 2.7.11.1   *Lim Kinases.
Limk2 protein, Xenopus  EC 2.7.11.1   *Xenopus Proteins *Lim Kinases.
Limk2 protein, rat  EC 2.7.11.1   *Lim Kinases.
LIMK2 protein, human  EC 2.7.11.1   *Lim Kinases. Biochem Biophys Res Commun 1996 Dec 13;229(2):582-9
Limk2 protein, mouse  EC 2.7.11.1   *Lim Kinases. Biochem Biophys Res Commun 1997 Dec 18;241(2):243-50; Oncogene 1995 Aug 17;11(4):711-21

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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