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Paxillin

More information in Books or onNLM PubMed
Definition: Paxillin is a signal transducing adaptor protein that localizes to FOCAL ADHESIONS via its four LIM domains. It undergoes PHOSPHORYLATION in response to integrin-mediated CELL ADHESION, and interacts with a variety of proteins including VINCULIN; FOCAL ADHESION KINASE; PROTO-ONCOGENE PROTEIN PP60(C-SRC); and PROTO-ONCOGENE PROTEIN C-CRK.     
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
pxn protein, zebrafish  0   *Zebrafish Proteins *Paxillin.
Pxn protein, rat  0   *Paxillin.
Pxn protein, mouse  0   *Paxillin.
PXN protein, human  0   *Paxillin.
paxillin protein, Xenopus  0   *Xenopus Proteins *Paxillin.
Pax protein, Drosophila  0   *Drosophila Proteins *Paxillin.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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