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Estradiol Congeners

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Definition: Steroidal compounds related to ESTRADIOL, the major mammalian female sex hormone. Estradiol congeners include important estradiol precursors in the biosynthetic pathways, metabolites, derivatives, and synthetic steroids with estrogenic activities.  GEN or unspecified; prefer specifics; do not confuse with ESTROGENS, CONJUGATED (USP)   
Examples Equilenin; Equilin; Estradiol; Estriol; Estrogenic Steroids, Alkylated; Estrogens, Catechol; Estrogens, Conjugated (USP); Estrogens, Esterified (USP); Estrone
Other names Analogues, Estrogen; Analogs, Estrogen; Synthetic Estrogens; Estrogens, Synthetic; Estrogen Analogues; Estrogen Analogs
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
estrogens, conjugated synthetic B  0   *Estradiol Congeners.
Pharma Action Estrogens
Obstet Gynecol. 2004 Feb;103(2):245-53.ENJUVIA
estrogens, conjugated synthetic A  0   *Estradiol Congeners.
Pharma Action Estrogens
Int J Fertil Womens Med. 2000 Jul-Aug;45(4):264-72.SYNTHETIC CONJUGATED ESTROGENS A; CENESTIN
17-(N,N'-diethylethylenediamine)-1,3,5(10)-estratrien-3-ol  0   *Estradiol Congeners. Proc West Pharmacol Soc 1998;41:179-82
nistranol  0   Ethinyl Estradiol/*analogs & derivatives Estradiol Congeners. Eksp Klin Farmakol 1997 Jul-Aug;60(4):25-8
Estratab  12126-59-9   *Estradiol Congeners. Obstet Gynecol 1993 Dec;82(6):919-24ESTRATAB
buame  137539-90-3 N-(3-hydroxy-1,3,5(10)-estratrien-17beta-yl)butylamine  Estradiol Congeners. Steroids 1993 Sep;58(9):407-9
pentolame  150748-24-6 17-beta-(5-hydroxy-1-pentylamino)-1,3,5(10)-estratrien-3-ol  *Amino Alcohols *Estrenes Estradiol Congeners. Proc West Pharmacol Soc 1993;36:143-7
16-hydroxy-equilenin  131944-03-1   Equilenin/*analogs & derivatives Estradiol Congeners. Steroids 1990;55(6):250
4-hydroxy-equilenin  81608-60-8   Equilenin/*analogs & derivatives Estradiol Congeners. Steroids 1990;55(6):250
4-hydroxy-equilin  81608-62-0   Equilin/*analogs & derivatives Estradiol Congeners. Steroids 1990;55(6):250
hexolame  110346-23-1 Estra-1,3,5(10)-trien-3-ol, 17-((6-hydroxyhexyl)amino)-, (17beta)  *Amino Alcohols *Estrenes Estradiol Congeners. Steroids 1990;55(2):83
estrynamine  115058-60-1   Estradiol/*analogs & derivatives Estradiol Congeners. Steroids 1986;48(3-4):223
17-hydroxy-3-methoxy-14,15-methylen-estra-1,3,5(a)-trien  73890-92-3   Estradiol/*analogs & derivatives Estradiol Congeners. Arch Int Pharmacodyn Ther 1986;283(1):5
17-(N,N,-dimethylhydrazinocarbonyloxy)estra-1,3,5(10)-trien-3-ol  55081-70-4   Estradiol/*analogs & derivatives Estradiol Congeners. Exp Clin Endocrinol 1985;86(3):257
prolame  99876-41-2 Estra-1,3,5(10)-trien-3-ol, 17-((3-hydroxypropyl)amino)-, (17beta)  *Estrenes Estradiol Congeners. Steroids 1985;45(2):151
11-bromomethyl-estradiol  90937-07-8 Estra-1,3,5(10)-triene-3,17-diol, 11-(bromomethyl)-, (11beta,17beta)  Estradiol/*analogs & derivatives Estradiol Congeners. Cancer Res 1984;44(6):2302
11-beta-chloromethyl-estradiol  71794-60-0   Estradiol/*analogs & derivatives Estradiol Congeners. Pharm Weekbl (Sci) 1983;5(4):182
prodiame  87189-13-7 Estra-1,3,5(10)-trien-3-ol, 17-((3-aminopropyl)amino)-, (17beta)  Estradiol Congeners. Proc West Pharmacol Soc 1983;26:111
Duogestral  0   *Progesterone Congeners Estradiol Congeners. Minerva Ginecol 1981;33(5):429
pamoestrol  78515-76-1 Pamoestrol  Estradiol Congeners. Wiad Lek 1980;33(10):787
17 beta-phenylaminocarbonyloxy-estra-1,3,5(10)-triene-3-methyl ether  43085-16-1   *Estrenes Estradiol Congeners. Arch Toxicol Suppl 1980;4:89-91; Verh Anat Ges 71(pt 1):655;1978; Zentralbl Gynakol 1978;100(22):1454-8
promestriene  39219-28-8 17 beta-methoxy-3-propoxyestra-1,3,5(10)-triene  Estradiol/*analogs & derivatives Estradiol Congeners. Am Ostet Ginecol Med Perinat 97(3):189;1976; Dermatologica 156:325;1978; Lille Med 22(9:suppl 2):736;1977; Sem Hop Ther 52(7-8):395;1976; Theropie 31(6):771;1976
nylestriol  39791-20-3 19-Norpregna-1,3,5(10)-trien-20-yne-16,17-diol, 3-(cyclopentyloxy)-, (16alpha,17alpha)  Quinestrol/*analogs & derivatives Estradiol Congeners. J Pharm Sci 64(7):1210;1975

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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