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Estrogens, Catechol

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Definition: 2- or 4-Hydroxyestrogens. Substances that are physiologically active in mammals, especially in the control of gonadotropin secretion. Physiological activity can be ascribed to either an estrogenic action or interaction with the catecholaminergic system.  /biosyn /physiol permitted   
Examples Hydroxyestrones
Other names Catechol Estrogens; Catecholestrogens
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
catechol estrogen 3,4-quinone  0   *Estrogens, Catechol. Chem Res Toxicol 1998 Nov;11(11):1339-45
6-hydroxyestrogen 6-sulfate  0   *Estrogens, Catechol Estrogens. Chem Res Toxicol 1998 Nov;11(11):1312-8
2-hydroxyestradiol 17-sulfate  75005-50-4   Estradiol/*analogs & derivatives Estrogens, Catechol. J Steroid Biochem 1989;32(6):823
2-hydroxymoxestrol  72226-93-8 19-Norpregna-1,3,5(10)-trien-20-yne-2,3,17-triol, 11-methoxy-, (11beta,17alpha)  Ethinyl Estradiol/*analogs & derivatives Estrogens, Catechol. FEBS Lett 1982;138(1):40
2-hydroxyestradiol-2,3-dibenzoate  79787-03-4 Estra-1,3,5(10)-triene-2,3,17-triol, 2,3-dibenzoate, (17beta)  Estradiol/*analogs & derivatives Estrogens, Catechol. Endocrinology 1981;109(4):1037
4-hydroxyestradiol-3,4-dibenzoate  79795-26-9 Estra-1,3,5(10)-triene-3,4,17-triol, 3,4-dibenzoate, (17beta)  Estradiol/*analogs & derivatives Estrogens, Catechol. Endocrinology 1981;109(4):1037
4-hydroxyestrone-3-methyl ether  5976-62-5   *Hydroxyestrones Estrogens, Catechol. Hoppe-Seylers Z Physiol Chem 1980;361(11):1743
4-hydroxyestrone-17-(O-carboxymethyl)oxime  77111-07-0 Acetic acid, (((3,4-dihydroxyestra-1,3,5(10)-trien-17-ylidene)amino)oxy)  *Hydroxyestrones Estrogens, Catechol. Hoppe Seylers Z Physiol Chem 1980;361(11):1743
4-hydroxyestrone  3131-23-5   *Hydroxyestrones Estrogens, Catechol. Steroids 1980;36(1):73
2-hydroxyestrone  362-06-1 Estra-1,3,5(10-trien-17-one, 2,3-dihydroxy)  *Hydroxyestrones Estrogens, Catechol.
Pharma Action Anticarcinogenic Agents
J Steroid Biochem 1980;13(1):83
4-hydroxyestriol  60021-32-1 Estra-1,3,5(10)-triene-3,4,16,17-tetrol, (16alpha,17beta)  Estriol/*analogs & derivatives Estrogens, Catechol. Steroids 28(5):733;1976
4-hydroxyestradiol-17 beta  5976-61-4   Estradiol/*analogs & derivatives Estrogens, Catechol. Steroids 28(5):733;1976
2-hydroxyestrone 2,3-methylene ether  53573-94-7 Estra-1,3,5(10)-trien-17-one, 2,3-(methylenebis(oxy))  *Hydroxyestrones Estrogens, Catechol. Steroids 23(6):869;1974
2-hydroxyestriol  1232-80-0 2,16 alpha-dihydroxyestradiol /OD/ estra-1,3,5(10)- triene-2,3,16 alpha,17 beta-tetrol  Estriol/*analogs & derivatives Estrogens, Catechol. Chem Pharm Bull (Tokyo) 23(7):1613;1975; J Endocrinol 1979;82(1):131; J Steroid Biochem 5(1):1;1974; J Steroid Biochem 6(7):1187;1975; Steroids 28(5):733;1976
2-hydroxyestradiol 2,3-methylene ether  53586-37-1 Estra-1,3,5(10)-trien-17-ol, 2,3-(methylenebis(oxy))-, (17beta)  Estradiol/*analogs & derivatives Estrogens, Catechol. Steroids 23(6):869;1974
2-hydroxyestradiol  362-05-0 (17 beta)-estra-1,3,5(10)-triene-2,3,17-triol  Estradiol/*analogs & derivatives Estrogens, Catechol. Arch Toxicol{suppl 2}321;1979; BBRC 78(3):919;1977; Biochem Biophys Res Com 70(4):1157;1976; Biochem Pharmacol 26:769;1977; Cancer Res 1979;39(12):4882; Endocrinology 1979;105(6):1288; Europ J Biochem 26(4):560;1972; Hoppe-Seyler's Z Physiol Chem 357(3):351;1976; J Am Med Wom Assoc 1979;34(10):363; J Biol Chem 253(14):4841;1978; J Biol Chem 254(13):5606;1979; J Endocrinol 1979;82(1):131; J Neurochem 1980;34(3):726; J Neurochem 31:245;1878; J Steroid Biochem 1979;11(1C):841; J Steroid Biochem 6(7):1187;1975; J Steroid Biochem 7(2):139;1976; J Steroids Biochem 8(8):835;1977; Life Sci 1980;26(9):743; Life Sci 20(3):419;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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