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Base Pair Mismatch

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Definition: The presence of an uncomplimentary base in double-stranded DNA caused by spontaneous deamination of cytosine or adenine, mismatching during homologous recombination, or errors in DNA replication. Multiple, sequential base pair mismatches lead to formation of heteroduplex DNA; (NUCLEIC ACID HETERODUPLEXES).     
See Also Base Pairing; Heteroduplex Analysis; Nucleic Acid Heteroduplexes 		Other names Mismatches, Base Pair; Mismatch, Base Pair; Base Pair Mismatches
 
SubstanceCAS Registry & nameCategoriesSource
Msh6 protein, C elegans  0   *DNA-Binding Proteins *Caenorhabditis elegans Proteins DNA Repair Base Pair Mismatch. Genetics 2005 May;170(1):107-13
MutLalpha protein, human  0   *DNA Repair Enzymes DNA Repair Base Pair Mismatch. Mol Carcinog 2005 May;43(1):51-8
MSH7 protein, Arabidopsis  0   *Arabidopsis Proteins DNA Repair Base Pair Mismatch.
Pms2 protein, mouse  EC 3.6.1.-   *Adenosine Triphosphatases *DNA-Binding Proteins *DNA Repair Enzymes DNA Repair Neoplasm Proteins Base Pair Mismatch.
Mbd4 protein, mouse  EC 3.2.2.-   *Endodeoxyribonucleases DNA Repair Base Pair Mismatch.
msh2 protein, S pombe  EC 3.6.1.3   *Schizosaccharomyces pombe Proteins *MutS Homolog 2 Protein DNA Repair Base Pair Mismatch.
CEL I nuclease  EC 3.1.30.-   *Endonucleases Plant Proteins Base Pair Mismatch. Biochemistry 2000 Apr 4;39(13):3533-41
MSH6 protein, Arabidopsis  0   *Arabidopsis Proteins DNA Repair Base Pair Mismatch. Mol Gen Genet 1999 Sep;262(2):239-49
MSH3 protein, Arabidopsis  0   *Arabidopsis Proteins DNA Repair Base Pair Mismatch. Mol Gen Genet 1999 Sep;262(2):239-49
MBD4 protein, human  EC 3.1.-   *Endodeoxyribonucleases Base Pair Mismatch. Proc Natl Acad Sci U S A 1999 Mar 30;96(7):3969-74
MutK protein, Vibrio cholerae  0   *Bacterial Proteins DNA Repair Base Pair Mismatch. J Bacteriol 1999 Feb;181(3):879-83
HSM3 protein, S cerevisiae  0   *Molecular Chaperones *Saccharomyces cerevisiae Proteins DNA Repair Base Pair Mismatch. Genetics 1998 Mar;148(3):963-73
MSH2 protein, Arabidopsis  EC 3.6.1.3   *Arabidopsis Proteins *MutS Homolog 2 Protein DNA Repair Base Pair Mismatch. Plant Physiol 1997 Oct;115(2):833-9
Msh6 protein, mouse  0   *DNA-Binding Proteins DNA Repair Base Pair Mismatch. Genomics 1996 Sep 1;36(2):288-95
PMS2 protein, human  EC 3.6.1.-   *Adenosine Triphosphatases *DNA-Binding Proteins *DNA Repair Enzymes DNA Repair Neoplasm Proteins Base Pair Mismatch. Cell 1995 Jul 28;82(2):309-19; Nature 1994 Sep 1;371(6492):75-80
G-T mismatch-binding protein  0   *DNA-Binding Proteins DNA Repair Base Pair Mismatch Zebrafish Proteins. Science 1995 Jun 30;268(5219):1912-4
Msh3 protein, mouse  0   *Proteins DNA Repair Base Pair Mismatch. Gene 1994 Sep 30;147(2):169-77
PMS1 protein, S cerevisiae  0   *Carrier Proteins *Saccharomyces cerevisiae Proteins DNA Repair Base Pair Mismatch. Science 1994 Aug 19;265(5175):1091-3
HexA protein, bacteria  0   *DNA-Binding Proteins *Bacterial Proteins DNA Repair Base Pair Mismatch. J Bacteriol 1993 Dec;175(23):7707-10
vsr endonuclease  EC 3.1.21.-   *Endodeoxyribonucleases DNA Repair Base Pair Mismatch. Nature 1991;353(6346):776
ampligen  38640-92-5   *Poly I-C *Poly U RNA, Double-Stranded Base Pair Mismatch.
Pharma Action Antiviral Agents 		J Biol Response Mod 1985;4(5):495

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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