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Xanthines
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Definition
: Purine bases found in body tissues and fluids and in some plants.
do not confuse with XANTHENES; XANTHINE is also available
Examples
Caffeine
;
Theobromine
;
Theophylline
;
Uric Acid
;
Xanthine
Substance
CAS Registry & name
Categories
Source
Drugs
*
bisdionin F
0
*Xanthines
Chitinase/antagonists & inhibitors.
Chem Biol 2011 May 27;18(5):569-79
1-
butyl-
8-
(3-
noradamantyl)-
3-
(3-
hydroxypropyl)xanthine
0
*Xanthines
Receptor, Adenosine A1.
Cell Biochem Funct 2008 Dec;26(8):833-43
xanthienopyran
0
*Pyrans
*Xanthines.
Planta Med. 2008 Aug;74(10):1276-9
xanthialdehyde
0
*Aldehydes
*Xanthines.
Planta Med. 2008 Aug;74(10):1276-9
cellulose xanthate
0
*Xanthines
Cellulose/*analogs & derivatives.
Carbohydr Res 1975 May;41:227-33
1,3-
dipropyl-
8-
(1-
phenylacetamide-
1H-
pyrazol-
3-
yl)-
xanthine
0
*Pyrazoles
*Xanthines.
Bioorg Med Chem. 2008 Mar 1;16(5):2419-30
NN 7201
0
*Xanthines.
Pharma Action
Dipeptidyl-Peptidase IV Inhibitors
Am J Physiol Gastrointest Liver Physiol 2007 Jul;293(1):G288-95
1-
propyl-
8-
(4-
sulfophenyl)xanthine
0
*Xanthines
Receptor, Adenosine A2B/antagonists & inhibitors.
J Med Chem 2004 Feb 12;47(4):1031-43
8-
(3-
Chlorostyryl)-
1,3,7-
trimethylxanthine
0
*Xanthines.
Acta Crystallogr C. 2005 Sep;61(Pt 9):o531-2
9-
butyl-
2-
(3-
noradamantyl)-
4,5-
dihydro-
6H,8H-
pyrimido(1,2,3-
cd)purine-
8,10-
dione
0
*Xanthines
Adamantane/*analogs & derivatives
Receptor, Adenosine A1/antagonists & inhibitors.
ChemMedChem 2006 Aug;1(8):891-902
1-
butyl-
3-
(3-
hydroxypropyl)-
8-
(3-
noradamantyl)xanthine
0
*Xanthines
Adamantane/*analogs & derivatives
Receptor, Adenosine A1/antagonists & inhibitors.
ChemMedChem 2006 Aug;1(8):891-902
8-
(4-
(4-
benzylpiperazide-
1-
sulfonyl)phenyl)-
1-
propylxanthine
0
*Sulfonamides
*Xanthines
Receptor, Adenosine A2B/antagonists & inhibitors.
J Med Chem 2006 Jul 13;49(14):4384-91
xanthophyll plectaniaxanthin
0
*Xanthines
*Xanthophylls.
Phytochemistry. 2005 Nov;66(22):2617-26
7-
(2-
(4-
(2-
nitrobenzene)piperazinyl)ethyl)-
1,3-
dimethylxanthine
0
*Piperidines
*Xanthines.
J Cardiovasc Pharmacol 2005 Nov;46(5):600-8
7-
(2-
(4-
(4-
nitrobenzene)piperazinyl)ethyl)-
1,3-
dimethylxanthine
0
*Piperidines
*Xanthines.
J Cardiovasc Pharmacol 2005 Nov;46(5):600-8
BG 9928
0
*Xanthines
Receptor, Adenosine A1.
Curr Opin Investig Drugs 2005 Sep;6(9):962-8
8-
(4-
(((1-
oxyl-
2,2,6,6-
tetramethylpiperidin-
4-
yl)amino)-
2-
oxoethoxy)phenyl)-
1-
propylxanthine
0
*Cyclic N-Oxides
*Xanthines.
J Med Chem 2005 Mar 24;48(6):2108-14
8-
(1-
oxyl-
2,2,5,5-
tetramethyl-
2,5-
dihydro-
1H-
pyrrol-
3-
yl)-
1,3-
dipropylxanthine
0
*Cyclic N-Oxides
*Xanthines.
J Med Chem 2005 Mar 24;48(6):2108-14
8-
cyclopentyl-
3-
(1-
oxyl-
2,2,5,5-
tetramethyl-
2,5-
dihydro-
1H-
pyrrol-
3-
ylmethyl)-
1-
propylxanthine
0
*Cyclic N-Oxides
*Xanthines.
J Med Chem 2005 Mar 24;48(6):2108-14
6,8-
dimethyl-
2-
piperidinomethyl-
2,3-
dihydrothiazolo(2,3-
f)xanthine
0
*Piperidines
*Thiazoles
*Xanthines.
Eksp Klin Farmakol. 2004 Jul-Aug;67(4):44-6
1-
methyl-
3-
propyl-
7-
N,N-
dimethylpropylamide-
xanthine
0
*Xanthines.
Toxicol Lett. 2004 May 2;150(3):341-9
1,7-
dimethyl-
8-
nitroxanthine
0
*Xanthines.
Cancer Sci 2004 Apr;95(4):361-6
1,8-
dibenzylxanthine
0
*Xanthines.
Bioorg Med Chem Lett. 2003 Nov 3;13(21):1871-4
8-
cyclopentyl-
3-
(3-
iodoprop-
2-
en-
1-
yl)-
1-
propylxanthine
0
*Xanthines
Iodine Radioisotopes
Receptor, Adenosine A1/antagonists & inhibitors.
Nucl Med Biol 2003 Aug;30(6)661-8
1-
butyl-
8-
(4-
((4-
nitrophenoxy)sulfonyl)phenyl)xanthine
0
*Sulfonic Acids
*Xanthines
Receptor, Adenosine A1/antagonists & inhibitors
Receptors, Adenosine A2/antagonists & inhibitors.
J Med Chem 2004 Feb 12;47(4):1031-43
1-
propyl-
8-
(4-
((4-
nitrophenoxy)sulfonyl)phenyl)xanthine
0
*Sulfonic Acids
*Xanthines
Receptor, Adenosine A1/antagonists & inhibitors
Receptors, Adenosine A2/antagonists & inhibitors.
J Med Chem 2004 Feb 12;47(4):1031-43
8-
cyclopenta-
3-
(3-
fluoropropyl)-
1-
propylxanthine
0
*Xanthines
Fluorine Radioisotopes
Receptors, Purinergic P1/antagonists & inhibitors.
J Med Chem 2002 Nov 7;45(23):5150-6
cipamfylline
0
*Xanthines
Phosphodiesterase Inhibitors.
Br J Pharmacol 2002 Aug;147(2):299-7
8-
hexylthio-
xanthine
0
Xanthines.
Farmaco 2001 Nov;56(11):809-13
1-
methyl-
8-
dicyclopropylmethyl-
1-
methyl-
3-
propylxanthine
0
*Xanthines
Carbon Radioisotopes.
Nucl Med Biol 2002 Jan;29(1):29-37
keto-
myxocoxanthin glucoside ester
0
*Carotenoids
*Xanthines.
Plant Cell Physiol 2001 Dec;42(12):1355-62
methoxy-
keto-
myxocoxanthin
0
*Carotenoids
*Xanthines.
Plant Cell Physiol 2001 Dec;42(12):1355-62
9-
ethyl-
8-
nitoxanthine
0
*Xanthines.
Chem Res Toxicol 2002 Jan;15(1):7-14
1-
(8-
phosphonooctyl)-
7-
deazaxanthine
0
*Xanthines
Thymidine Phosphorylase/antagonists & inhibitors.
FEBS Lett 2002 Jan 2;510(1-2):83-8
KMCP 98
0
*Xanthines
Receptors, Purinergic P1/agonists.
Gen Pharmacol 2000 Jul;35(1):47-57
3-
isobutyl-
8-
pyrrolidinoxanthine
0
*Pyrrolidinones
*Xanthines.
Biochem Pharmacol 2001 Nov 1;62(9):1163-73
KMUP 1
0
*Xanthines
*Piperidines.
Br J Pharmacol 2001 Sep;134(2):265-74
5-
aza-
7-
deazaxanthine
0
*Aza Compounds
*Xanthines.
J Org Chem 2001 Jul 27;66(15):5012-5
8-
Nitroxanthine
0
*Xanthines.
Chem Res Toxicol 2001 May;14(5):536-46
8-
cyclopentyl-
3-
(3-
(4-
fluorosulfonylbenzamido)propyl)-
1-
propylxanthine
0
*Xanthines
Receptors, Purinergic P1/antagonists & inhibitors.
J Med Chem 2000 Dec 28;43(26):4973-80
X 33 compound
0
*Xanthines.
Am J Physiol Cell Physiol 2000 Dec;279(6):C1925-37
(H(3))3-
(3-
hydroxypropyl)-
7-
methyl-
8-
(m-
methoxystyryl)-
1-
propargylxanthine
0
*Styrenes
*Xanthines.
Eur J Pharm Sci 2000 ;10(4):259-65
MRS 1595
0