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Autacoids

More information in Books or onNLM PubMed
Definition: A chemically diverse group of substances produced by various tissues in the body that cause slow contraction of smooth muscle; they have other intense but varied pharmacologic activities.  slow-reacting substances: note X ref; GEN or unspecified; prefer specifics   
Examples Angiotensins; Eicosanoids; Histamine; Kinins; Platelet Activating Factor; Serotonin 		Other names Slow-Reacting Substances; Substances, Slow-Reacting; Slow Reacting Substances
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
leukotriene D-3  77165-74-3 Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6-pentadecatrienyl)-L-cysteinyl)-, (R-(R*,S*-(E,E,Z)))  SRS-A/*analogs & derivatives Autacoids. J Biol Chem 1981;256(5):2275
leukotriene C-3  77209-77-9 Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6-pentadecatrienyl)-N-L-gamma-glutamyl-L-cysteinyl)-, (R-(R*,S*-(E,E,Z)))  SRS-A/*analogs & derivatives Autacoids. J Biol Chem 1981;256(5):2275
lysyl-phenylalanyl-isoleucyl-glycyl-leucyl-methioninamide  2990-43-4   *Oligopeptides Autacoids. Acta Biol Med Ger 1980;39(1):141
leukotriene C-5  75207-09-9 Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9,12-pentadecapentaenyl)-N-L-gamma-glutamyl-L-cysteinyl)-, (R-(R*,S*-(E,E,Z,Z,Z)))  SRS-A/*analogs & derivatives Eicosapentaenoic Acid/*analogs & derivatives Autacoids. J Biol Chem 1980;255(15):7093
leukotriene C-2  74841-69-3 Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)-, (R-(R*,S*-(E,E,E,Z)))  SRS-A/*analogs & derivatives Autacoids. Biochem Biophys Res Commun 1980;94(4):1133
substance P-like peptides  0   *Peptides Autacoids Substance P. Acta Physiol Pol 28(5):397;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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