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Eicosanoids

More information in Books or onNLM PubMed
Definition: A class of compounds named after and generally derived from C20 fatty acids (EICOSANOIC ACIDS) that includes PROSTAGLANDINS; LEUKOTRIENES; THROMBOXANES, and HYDROXYEICOSATETRAENOIC ACIDS. They have hormone-like effects mediated by specialized receptors (RECEPTORS, EICOSANOID).  GEN or unspecified; prefer specifics   
See Also Receptors, Eicosanoid
Examples Arachidonic Acids; Eicosapentaenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; 8,11,14-Eicosatrienoic Acid; Lipoxins; Prostaglandins; Thromboxanes 		Other names Icosanoids
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
(8-hydroxymethylen)trieicosanyl acetate  0   *Acetates *Eicosanoids. Phytomedicine 2008 Oct;15(10):892-5
14-ethyl-2,5,11-trimethyl-4,13,19,20-tetraoxa-tricyclo(14.2.1.1(7,10))eicosane-3,12-dione  0   *Eicosanoids *Macrolides. Mol Cancer Ther. 2007 Nov;6(11):3059-70
solandelactone F  0   *Lactones *Eicosanoids Cyclopropanes. Org Lett 2007 Aug 16;9(17):3481-3
methyl 6-eicosanyl-2-hydroxy-4-methoxybenzoate  0   *Benzoates *Eicosanoids. Nat Prod Res. 2005 Jul;19(5):431-3
FPR2 protein, human  0   *Receptors, Formyl Peptide *Receptors, Lipoxin Eicosanoids. Adv Exp Med Biol 1999;447:133-49; J Biol Chem 1997 Mar 14;272(11):6972-8
lipoxin C4  85951-62-8 Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-10-hydroxy-2,4,6,8-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)-, (1R-(1R*,1(S*),2E,4E,6Z,8E,10S*))  *Oligopeptides *Eicosanoids. J Chromatogr 1991 Oct 25;585(1):53-6
U 49619  130463-95-5   *Eicosanoids Prostaglandin Antagonists. Neuroendocrinology 1989;50(6):708

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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