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Receptors, Progesterone

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Definition: Specific proteins found in or on cells of progesterone target tissues that specifically combine with progesterone. The cytosol progesterone-receptor complex then associates with the nucleic acids to initiate protein synthesis. There are two kinds of progesterone receptors, A and B. Both are induced by estrogen and have short half-lives.  coord IM with specific progesterone (IM); DF: RECEPT PROGESTERONE    Other names Receptors, Progestin; Progestin Receptors; Progesterone Receptors; Receptor, Progesterone; Progesterone Receptor
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PAQR5 protein, human  0   *Receptors, Progesterone. Horm Cancer. 2010 Aug;1(4):167-76
PAQR7 protein, human  0   *Receptors, Progesterone. Horm Cancer. 2010 Aug;1(4):167-76
4-(3-cyclopropyl-1-(methylsulfonylmethyl)-5-methyl-1H-pyrazol-4-yl)oxy-2,6-dimethylbenzonitrile  0   *Pyrazoles *Sulfones Receptors, Progesterone/antagonists & inhibitors. Drug Metab Dispos. 2011 Aug;39(8):1396-405.
adipoQ receptor 8, rat  0   *Receptors, Progesterone. Neuroscience 2011 Jan 13;172:55-65
adipoQ receptor 7, rat  0   *Receptors, Progesterone. Neuroscience 2011 Jan 13;172:55-65
CP 8947  0   *Indoles Receptors, Progesterone. J Steroid Biochem Mol Biol 2010 Oct;122(4):279-86
3-(4-nitrophenylamino)-3-(3-fluorophenyl)-1-p-tolylpropan-1-one  0   *Aniline Compounds *Chalcones Receptors, Progesterone/antagonists & inhibitors. Bioorg Med Chem 2010 Jun 15;18(12):4255-68
17-methyl-16-phenyl-17-(3-fluorophenyl)acetoxyhomoandrost-4,6-diene-3,17a-dione  0   *Homosteroids Androstenedione/*analogs & derivatives Receptors, Progesterone/antagonists & inhibitors. Steroids 2010 Jan;75(1):101-8
17-methyl-16-phenyl-17-(2-fluorophenyl)acetoxyhomoandrost-4,6-diene-3,17a-dione  0   *Homosteroids Androstenedione/*analogs & derivatives Receptors, Progesterone/antagonists & inhibitors. Steroids 2010 Jan;75(1):101-8
17-methyl-16-phenyl-17-phenylacetoxyhomoandrost-4,6-diene-3,17a-dione  0   *Homosteroids Androstenedione/*analogs & derivatives Receptors, Progesterone/antagonists & inhibitors. Steroids 2010 Jan;75(1):101-8
Pgrmc2 protein, rat  0   *Membrane Proteins *Receptors, Progesterone. Endocrinology 2009 Jul;150(7):3186-96
PAQR9 protein, human  0   *Receptors, Progesterone. Steroids 2008 Oct;73(11):1160-73
PAQR6 protein, human  0   *Receptors, Progesterone. Steroids 2008 Oct;73(11):1160-73
7,9-difluoro-5-(3-methylcyclohex-2-enyl)-2,2,4-trimethyl-1,2-dihydrochromeno(3,4-f)quinoline  0   *Benzopyrans *Quinolines Receptors, Progesterone. J Med Chem 2008 Jul 10;51(13):3696-9
TNRC9 protein, human  0   *Receptors, Progesterone. Nature 2007 Jun 28;447(7148):1087-93
membrane progestin receptor gamma, human  0   *Receptors, Progesterone *Receptors, G-Protein-Coupled. Mol Endocrinol 2006 Dec;20(12):3146-64
membrane progestin receptor beta, human  0   *Receptors, Progesterone *Receptors, G-Protein-Coupled. Mol Endocrinol 2006 Jul;20(7):1519-34
membrane progestin receptor alpha, human  0   *Receptors, Progesterone *Receptors, G-Protein-Coupled. Mol Endocrinol 2006 Jul;20(7):1519-34
mPR-beta protein, zebrafish  0   *Receptors, Progesterone *Zebrafish Proteins. Proc Natl Acad Sci U S A 2003 Mar 4;100(5):2237-42
mPR-alpha protein, zebrafish  0   *Receptors, Progesterone *Zebrafish Proteins. Proc Natl Acad Sci U S A 2003 Mar 4;100(5):2237-42
PGRMC1 protein, mouse  0   *Membrane Proteins *Receptors, Progesterone. Biochemistry 2005 Dec 20;44(50):16729-36
tanaproget  0   *Thiones *Benzoxazines Receptors, Progesterone/agonists. J Biol Chem 2005 Aug 5;280(31):28468-75
tanoproget  0   *Pyrroles *Benzoxazines Receptors, Progesterone/agonists. J Med Chem 2005 Aug 11;48(16):5092-5
pr2 protein, Xenopus  0   *Receptors, Progesterone *Xenopus Proteins. Dev Biol 2005 Jul 1;283(1):180-90
TEBP protein, human  0   *Phosphoproteins *Molecular Chaperones Receptors, Progesterone.
Pgrmc1 protein, rat  0   *Membrane Proteins *Receptors, Progesterone.
Nrbf1 protein, rat  0   *DNA-Binding Proteins *Intracellular Signaling Peptides and Proteins Nuclear Proteins Receptors, Progesterone.
PAQR8 protein, human  0   *Nerve Tissue Proteins *Receptors, Progesterone. Biochem Biophys Res Commun 2001 Nov 2;288(3):626-36
XPR-1 protein, Xenopus  0   *Receptors, Progesterone *Xenopus Proteins. Proc Natl Acad Sci U S A 2000 Dec 19;97(26):14358-63
ZK 230211  0   *Estrenes Receptors, Progesterone/antagonists & inhibitors. J Med Chem 2000 Dec 28;43(26):5010-6
1,2-dihydro-5-(2-methylbenzylidene)-2,2,4-trimethyl-5H-chromeno(3,4-f)quinoline  0   *Benzopyrans *Quinolines Receptors, Progesterone/agonists. J Med Chem 1998 Oct 22;41(22):4354-9
5-(3-fluorobenzylidene)-1,2-dihydro-2,2,4-trimethyl-5H-chromeno(3,4-f)quinoline  0   *Benzopyrans *Quinolines Receptors, Progesterone/agonists. J Med Chem 1998 Oct 22;41(22):4354-9
PGRMC2 protein, human  0   *Membrane Proteins *Receptors, Progesterone. Biol Chem 1998 Jul;379(7):907-11
PGRMC1 protein, human  0   *Membrane Proteins *Receptors, Progesterone. Biol Chem 1998 Jul;379(7):907-11
LG 120753  0   *Quinolines Receptors, Progesterone/antagonists & inhibitors. J Med Chem 1998 Aug 27;41(18):3461-6
LG 120830  0   *Quinolines Receptors, Progesterone/antagonists & inhibitors. J Med Chem 1998 Aug 27;41(18):3461-6
LG 120747  0   *Benzopyrans *Quinolines Receptors, Progesterone/antagonists & inhibitors. J Med Chem 1998 Jul 16;41(15):2779-85
LG 120746  0   *Benzopyrans *Quinolines Receptors, Progesterone/antagonists & inhibitors. J Med Chem 1998 Jul 16;41(15):2779-85
16,17-cyclopropanoprogesterone  0   Progesterone/*analogs & derivatives Receptors, Progesterone/agonists. Biull Eksp Biol Med 1998 May;125(5):532-4
RU 46534  0   Mifepristone/*analogs & derivatives Progestins/antagonists & inhibitors Receptors, Progesterone/antagonists & inhibitors. J Reprod Fertil Suppl 1997;51:317-25
PF 1092C  0 (4aR,5R,6R,7S)-6,7-dihydroxy-4a,5,6,7-tetrahydro-3,4a,5-trimethylnaphtho(2,3-b)furan-2(4H)-one  *Naphthols *Sesquiterpenes Hormone Antagonists Receptors, Progesterone. J Antibiot (Tokyo) 1997 Apr;50(4):309-13
PF 1092B  0   *Naphthols *Sesquiterpenes Hormone Antagonists Receptors, Progesterone. J Antibiot (Tokyo) 1997 Apr;50(4):309-13
PF 1092A  0 (4aR,5R,6R,7S)-6-acetoxy-7-hydroxy-4a,5,6,7-tetrahydro-3,4a,5-trimethylnaphtho(2,3-b)furan-2(4H)-one  *Naphthols *Sesquiterpenes Hormone Antagonists Receptors, Progesterone. J Antibiot (Tokyo) 1997 Apr;50(4):309-13
progesterone receptor A  0   *Receptors, Progesterone. Mol Endocrinol 1996 Apr;10(4):393-407
progesterone receptor B  0   *Receptors, Progesterone. J Biol Chem 1995 Dec 22;270(51):30693-700
RBF-1 protein, Gallus gallus  0   *Carrier Proteins *DNA-Binding Proteins *Avian Proteins Nuclear Proteins Receptors, Progesterone. J Cell Biochem 1993 Dec;53(4):383-93
21-chlorodanazol  121565-23-9   Danazol/*analogs & derivatives Receptors, Progesterone. Yao Hsueh Hsueh Pao 1988;23(11):860
21-chloro-6-dehydrodanazol  121565-24-0   Danazol/*analogs & derivatives Receptors, Progesterone. Yao Hsueh Hsueh Pao 1988;23(11):860

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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