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Pyridoxal

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Definition: The 4-carboxyaldehyde form of VITAMIN B 6 which is converted to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.  deficiency: coordinate PYRIDOXAL /defic (IM) with VITAMIN B 6 DEFICIENCY (IM)   
Pharmacological Action Vitamin B Complex
Examples Pyridoxal Phosphate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
pyridoxylidene aminoguanidine  0   *Guanidines *Pyridoxal. Gen Physiol Biophys. 2009 Dec;28(4):347-55
4-pyridoxolactone  0   Pyridoxal/*analogs & derivatives. J Biosci Bioeng 2008 Nov;106(5):460-5
1,3-dioleoyl-2-phosphatidylethanolamine pyridoxal Schiff base adduct  0   *Phosphatidylethanolamines Pyridoxal/*analogs & derivatives. J Lipid Res 2006 May;47(5):964-74
pyridoxal 2-chlorobenzoyl hydrazone  0   *Hydrazones Pyridoxal/*analogs & derivatives. Hum Exp Toxicol 2005 Nov;24(11):581-9
pyridoxal-4-phenyl-3-thiosemicarbazone  0   *Thiosemicarbazones Pyridoxal/*analogs & derivatives. J Agric Food Chem. 2005 Jul 13;53(14):5492-8
L-methionine ethyl ester-pyridoxal  0   Methionine/*analogs & derivatives Pyridoxal/*analogs & derivatives. Bull Cancer 2004 Apr;91(4) (dup#1):E61-79
aminoguanidine pyridoxal adduct  0   *Guanidines Pyridoxal/*analogs & derivatives. Horm Metab Res 2002 Jul;34(7):371-7
pyridoxylidenelysine  0   *Pyridoxal Lysine/*analogs & derivatives. J Agric Food Chem 2001 Mar;49(3):1559-63
5'-pyridoxal 5'-difluoromethylenephosphonic acid  0   *Phosphonic Acids Pyridoxal/*analogs & derivatives. Biochemistry 1996 Nov 26;35(47):15057-64
5'-deoxypyridoxal 5'-methylenephosphonic acid  19730-75-7   *Phosphonic Acids Pyridoxal/*analogs & derivatives. Biochemistry 1996 Nov 26;35(47):15057-64
pedoxin  158365-17-4 4H-Pyrido(4,3-f)(1,4)oxazocin-4-one, 3,6-dihydro-10-hydroxy-9-methyl  Pyridoxal/*analogs & derivatives Marine Toxins. J Biol Chem 1994 Oct 28;269(43):26734-38
N-(4'-pyridoxyl)sphingosine  149590-30-7   Pyridoxal/*analogs & derivatives Sphingosine/*analogs & derivatives. Membr Biochem 1993 Jan-Mar;10(1):53-9
pyridoxal thiosemicarbazone  3814-80-0 Hydrazinecarbothioamide, 2-((3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl)methylene)  *Thiosemicarbazones Pyridoxal/*analogs & derivatives. Boll Soc Ital Biol Sper 1991 Jul;67(7):673-80
pyridoxal 3-fluorobenzoyl hydrazone  116324-91-5   *Hydrazones Pyridoxal/*analogs & derivatives. Biol Met 1989;2(2):69
pyridoxal 4-methoxybenzoyl hydrazone  116324-89-1   *Hydrazones Pyridoxal/*analogs & derivatives. Biol Met 1989;2(2):69
dichlorobispyridoxalpalladium (II)  84206-78-0   *Organometallic Compounds Pyridoxal/*analogs & derivatives Palladium. Microbios 1990;62(252-254):165
pyridoxal benzoyl hydrazone  72343-06-7   *Hydrazones Pyridoxal/*analogs & derivatives. Biochem Pharmacol 1990;39(11):1665
6-fluoro-5'-deoxypyridoxal  106212-90-2   Pyridoxal/*analogs & derivatives. Biochemistry 1987;26(2):360
pyridoxal 3-sulfate  107467-08-3   Pyridoxal/*analogs & derivatives. J Biol Chem 1987;262(6):2642
adenosine tetraphosphopyridoxal  101418-64-8   *Adenine Nucleotides Pyridoxal/*analogs & derivatives. Biochemistry 1986;25(10):2958
6-fluoropyridoxal  42242-42-2   Pyridoxal/*analogs & derivatives. J Biol Chem 1985;260(5):2709
technetium Tc 99m N-pyridoxylidenehydrazine-N',N'-diacetic acid  0   *Organotechnetium Compounds Pyridoxal/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1984;32(6):2262
1-dodecylpyridoxal  87251-90-9 Pyridinium, 1-dodecyl-4-formyl-3-hydroxy-5-(hydroxymethyl)-2-methyl-, chloride  Pyridoxal/*analogs & derivatives. Prog Clin Biol Res 1984;144A:101
5-(2-phosphonoethyl)pyridoxal  32555-98-9   Pyridoxal/*analogs & derivatives. Neuropharmacology 1983;22(7):865
technetium Tc 99m pyridoxyl-5-methyltryptophan  0   *Organotechnetium Compounds Pyridoxal/*analogs & derivatives Tryptophan/*analogs & derivatives.
Pharma Action Radiopharmaceuticals 		Radioisotopes 1983;32(1):26
pyridoxal methyloxime  26323-27-3   Pyridoxal/*analogs & derivatives. J Chromatogr 1982;250:86
pyridoxal 5'-sulfate  40225-35-2 4-Pyridinecarboxaldehyde, 3-hydroxy-2-methyl-5-((sulfooxy)methyl)  Pyridoxal/*analogs & derivatives. Biochemistry 1982;21(21):5213
5-phosphopyridoxal-aminooxyacetate  83351-95-5 4-Pyridinecarboxaldehyde, 3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-, O-acetyloxime  Pyridoxal/*analogs & derivatives 4-Aminobutyrate Transaminase/antagonists & inhibitors. Eur J Biochem 1982;126(3):507
pyridoxaloxime  708-08-7   Pyridoxal/*analogs & derivatives. J Biol Chem 1980;256(2):780
pyridoxal 5'-deoxymethylenephosphonate  75790-54-4 Phosphonic acid, mono(2-(4-formyl-5-hydroxy-6-methyl-3-pyridinyl)ethyl) ester  Pyridoxal/*analogs & derivatives. Biochem Biophys Res Commun 1980;95(4):1832
pyridoxylideneaminate  0   Pyridoxal/*analogs & derivatives. J Nucl Med 1980;20(10):1071
pyridoxal-gamma-aminobutyrate imine  0   gamma-Aminobutyric Acid/*analogs & derivatives Pyridoxal/*analogs & derivatives. J Biol Chem 255(1):79;1980
pyridoxal isonicotinoyl hydrazone  737-86-0 4-pyridinecarboxylic acid, ((3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl)methylene)hydrazide  Isoniazid/*analogs & derivatives Pyridoxal/*analogs & derivatives.
Pharma Action Chelating Agents ; Iron Chelating Agents 		Biochim Biophys Acta 586(2):278;1979; FEBS Lett 97(2):317;1979
4-vinylpyridoxal  0   Pyridoxal/*analogs & derivatives. Biochem Pharmacol 28(13):1669;1979
epsilon-pyridoxyllysine  3564-92-9   Lysine/*analogs & derivatives Pyridoxal/*analogs & derivatives. J Biol Chem 1980;255(6):2355; J Nutr 108(7):1192;1978
alpha(5)-pyridoxalphenylalanine acetic acid  23847-74-7 3-Pyridinepropanoic acid, 4-(((1-carboxy-2-phenylethyl)amino)methyl)-5-hydroxy-6-methyl-, (S)  Pyridoxal/*analogs & derivatives. Experientia 31(9):1017;1975
alpha-5-pyridoxalacetic acid  16133-22-5   Pyridoxal/*analogs & derivatives. Boll Soc Ital Biol Sper 50(23-24):2005;1975; Experientia 31(9):1017;1975
alpha-4-norpyridoxal  7442-74-2   Pyridoxal/*analogs & derivatives. Chem Pharm Bull (Tokyo) 24(5):1089;1976; J Org Chem 40(8):1051;1975
pyridoxal 5'-methylenephosphonate  26210-18-4   Pyridoxal/*analogs & derivatives. Biochem Biophys Res Commun 57(4):1166;1974
4-desoxyisopyridoxal  32453-97-7   Pyridoxal/*analogs & derivatives. J Med Chem 14(7):568;1971
4-deformyl-4-vinylpyridoxal  42381-06-6   Pyridoxal/*analogs & derivatives. J Med Chem 16(7):865;1973
alpha-5-pyridoxal methyl chloride  41656-90-0 5-(2-chloroethyl)-3-hydroxy-2-methyl-4-pyridinecarboxaldehyde  Pyridoxal/*analogs & derivatives. Biochemistry 11(26):4945;1972
5-deoxypyridoxal  1849-49-6 3-hydroxy-2,5-dimethyl-4-pyridinecarboxaldehyde  Pyridoxal/*analogs & derivatives. Biochem Biophys Res Commun 1980;92(1):155; Biochemistry 11(15):2911;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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