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Prostaglandins

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Definition: A group of compounds derived from unsaturated 20-carbon fatty acids, primarily arachidonic acid, via the cyclooxygenase pathway. They are extremely potent mediators of a diverse group of physiological processes.  GEN or unspecified only: prefer specifics; /biosyn /physiol permitted; /chem syn permitted: do not convert to PROSTAGLANDINS, SYNTHETIC   
See Also Prostaglandin Antagonists; Receptors, Prostaglandin
Examples Prostaglandin Endoperoxides; Prostaglandins A; Prostaglandins B; Prostaglandins D; Prostaglandins E; Prostaglandins F; Prostaglandins I 		Other names Prostanoids
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
delta12-prostaglandin J3  0   *Prostaglandins *Fatty Acids, Omega-3 Leukemia/drug therapy. Blood. 2011 Dec 22;118(26):6909-19
tetranor prostaglandin M  0   *Prostaglandins. J Chromatogr B Analyt Technol Biomed Life Sci 2008 Aug 1;871(1):72-7
bromovulone III  0   *Prostaglandins. Eur J Pharmacol. 2006 Aug 7;542(1-3):22-30
carijenone  0   *Prostaglandins *Bicyclo Compounds, Heterocyclic. Org Lett. 2004 Jun 24;6(13):2229-32
claviridenone G  0   *Prostaglandins. J Nat Prod 2002 Nov;65(11):1535-9
claviridenone F  0   *Prostaglandins. J Nat Prod 2002 Nov;65(11):1535-9
claviridenone E  0   *Prostaglandins. J Nat Prod 2002 Nov;65(11):1535-9
clavubicyclone  0   *Prostaglandins. J Org Chem 2002 May 3;67(9):2977-81
tricycloclavulone  0   *Prostaglandins. J Org Chem 2002 May 3;67(9):2977-81
NEPP6-biotin  0   *Prostaglandins Biotin/*analogs & derivatives. J Neurochem 2001 Apr;77(1):50-62
NEPP6 compound  0   *Prostaglandins. J Neurochem 2001 Apr;77(1):50-62
S 1033  0   *Prostaglandins. Nippon Ganka Gakkai Zasshi 1994 Nov;98(11):1109-14
RS 61756-007  121571-14-0   *Prostaglandins. J Pharm Pharmacol 1989;41(5):347
7-hydroxy-5,11-dioxotetranorprostane-1,16-dioic acid  73303-30-7   *Prostaglandins. Lipids 1989;24(5):419
MR 256  119314-69-1   *Prostaglandins. Cell Biochem Funct 1989;7(2):105
2-chloro-4-hydroxy-5-(6-methoxycarbonyl-2-hexyenylidene)-4-n-octyl-2-cyclopentanone  0   *Prostaglandins. Jpn J Ophthamol 1987;31(4):598
4-fluoroenisoprost  109976-45-6   *Prostaglandins. J Med Chem 1987;30(11):1952
4-(3-((2-(1-hydroxycyclohexyl)ethyl)-4-oxo-2-thiazolidinyl)propyl)benzoic acid  72313-44-1 Benzoic acid, 4-(3-(3-(2-(1-hydroxycyclohexyl)ethyl)-4-oxo-2-thiazolidinyl)propyl)  *Thiazolidines Prostaglandins. J Pharmacol Exp Ther 1982;222(1):152
AY 22093  24341-38-6 9-oxo-15-hydroxyprostanoic acid  *Prostaglandins. Can J Phys Pharmacol 52(1):1;1974

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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