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Receptors, Prostaglandin

More information in Books or onNLM PubMed
Definition: Cell surface receptors that bind prostaglandins with high affinity and trigger intracellular changes which influence the behavior of cells. Prostaglandin receptor subtypes have been tentatively named according to their relative affinities for the endogenous prostaglandins. They include those which prefer prostaglandin D2 (DP receptors), prostaglandin E2 (EP1, EP2, and EP3 receptors), prostaglandin F2-alpha (FP receptors), and prostacyclin (IP receptors).  coord IM with specific natural or synthetic prostaglandin (IM); RECEPTORS, PROSTAGLANDIN E is available; DF: RECEPT PG   
Examples Receptors, Epoprostenol; Receptors, Prostaglandin E; Receptors, Thromboxane A2, Prostaglandin H2
Other names Prostaglandin Receptors; Prostaglandins Receptors; Receptors, Prostaglandins; Receptor, Prostaglandin; Prostaglandin Receptor
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
(2'-(3-benzyl-1-ethylureidomethyl)-6-methoxy-4'-trifluoromethylbiphenyl-3-yl)acetic acid  0   *Methylurea Compounds *Phenylacetates Receptors, Prostaglandin/antagonists & inhibitors. J Pharmacol Exp Ther 2011 Jul;338(1):290-301
(2'-((cyclopropanecarbonylethylamino)methyl)-4'-(6-ethoxy-pyridin-3-yl)-6-methoxybiphenyl-3-yl)acetic acid  0   *Phenylacetates *Pyridines Receptors, Prostaglandin/antagonists & inhibitors. Bioorg Med Chem Lett 2011 Feb 1;21(3):1036-40
CAY 10471  0   *Carbazoles *Sulfonamides Receptors, Prostaglandin/antagonists & inhibitors. Biochem Biophys Res Commun 2008 Dec 19;377(3):878-83
prostanoid D receptor 1, mouse  0   *Receptors, Prostaglandin. J Immunol 2008 Jan 15;180(2):783-92
THG113.31 peptide  0   *Peptides Receptors, Prostaglandin/antagonists & inhibitors. Am J Obstet Gynecol 2005 Jul;193(1):256-66
prostanoid D receptor 1, human  0   *Receptors, Prostaglandin. Crit Rev Immunol 2004;24(5):349-62
Ptgir protein, mouse  0   *Receptors, Prostaglandin.
Ptgir protein, rat  0   *Receptors, Prostaglandin.
PTGFRN protein, human  0   *Neoplasm Proteins Receptors, Prostaglandin.
EP3C receptor  0   *Receptors, Prostaglandin. J Biol Chem 2001 May 11;276(19):16083-91
16-(3-chlorophenoxy)-9,11a,15-trihydroxy-17,18,19,20-tetranor-11a-homo-5,13-prostadienoic acid  0   Cloprostenol/*analogs & derivatives Receptors, Prostaglandin/agonists. J Med Chem 2000 Sep 7;43(18):3400-7
AL 8810  0   Dinoprost/*analogs & derivatives Receptors, Prostaglandin/antagonists & inhibitors. J Pharmacol Exp Ther 1999 Sep;290(3):1278-84
PTGIR protein, human  0   *Receptors, Prostaglandin. Mol Pharmacol 1998 Aug;54(2):249-57
Ptgfrn protein, rat  0   *Neoplasm Proteins Receptors, Prostaglandin. J Biol Chem 2001 Apr 27;276(17):14329-37; Prostaglandins Leukot Essent Fatty Acids 1996 Oct;55(4):261-68
BW 572C85  0   *Butyric Acids *Imidazoles Receptors, Prostaglandin/agonists. Bioorg Med Chem 1996 Jan;4(1):81-90
BW 480C85  0   *Butyric Acids *Imidazoles Receptors, Prostaglandin/agonists. Bioorg Med Chem 1996 Jan;4(1):81-90
BW 587C  0   *Butyric Acids *Imidazoles Receptors, Prostaglandin/agonists. Bioorg Med Chem 1996 Jan;4(1):81-90
BW A868C  118675-50-6 4-Imidazolidineheptanoic acid, 3-((2-cyclohexyl-2-hydroxyethyl)amino)-2,5-dioxo-1-(phenylmethyl)  *Hydantoins Receptors, Prostaglandin/antagonists & inhibitors.
Pharma Action Platelet Aggregation Inhibitors
Br J Pharmacol 1989;96(2):291
prostaglandin endoperoxide receptor  0   *Receptors, Prostaglandin. Eur J Clin Invest 1988;18(1):1
prostaglandin D2 receptor  0   *Receptors, Immunologic *Receptors, Prostaglandin Pregnancy Proteins Prostaglandin D2. Biochem Biophys Res Commun 2003 Aug 8;307(4):797-802; Gene 1999 Feb 4;227(1):71-7; J Biol Chem 1982;257(22):13570
prostaglandin F2alpha receptor  0   *Receptors, Prostaglandin Dinoprost. Arch Biochem Biophys 1982;214(2):431
BW 245C  75693-75-3   *Hydantoins Receptors, Prostaglandin/agonists. Neuropharmacology 1981;20(5):517

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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