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Prolactin

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Definition: A lactogenic hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). It is a polypeptide of approximately 23 kD. Besides its major action on lactation, in some species prolactin exerts effects on reproduction, maternal behavior, fat metabolism, immunomodulation and osmoregulation. Prolactin receptors are present in the mammary gland, hypothalamus, liver, ovary, testis, and prostate.  /blood: consider also HYPERPROLACTINEMIA   
See Also Hyperprolactinemia; Receptors, Prolactin 		Other names Mammotropin; Mammotropic Hormone, Pituitary; Lactogenic Hormone, Pituitary; Pituitary Mammotropic Hormone; Pituitary Lactogenic Hormone; Hormone, Pituitary Mammotropic; Hormone, Pituitary Lactogenic; PRL (Prolactin)
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
prolactin, delta(1-9)-Arg(129)  0   Prolactin/*analogs & derivatives Receptors, Prolactin/antagonists & inhibitors. Endocr Rev 2005 May;26(3):400-22
prolactin 16-kDa fragment, human  0   *Peptide Fragments *Prolactin. Mol Endocrinol 2005 Jul;19(7):1932-42
Dtprp protein, mouse  0   Prolactin/*analogs & derivatives.
1-methyl-3,4-dihydroisoquinoline  0   *Isoquinolines Prolactin/antagonists & inhibitors. J Neuroendocrinol. 2004 Mar;16(3):208-13
thyrostimulin  0   *Glycoproteins Follicle Stimulating Hormone Prolactin Thyrotropin. J Clin Invest 2002 Jun;109(11):1445-52
prolactin, Asp(179)  0   *Prolactin Receptors, Prolactin/antagonists & inhibitors. Endocrinology 2001 Feb;142(2):730-9
prolactin, Arg(129)  0   *Prolactin Prolactin/antagonists & inhibitors. Clin Cancer Res 1999 Nov;5(11):3583-93
PLP-I protein, rat  0   *Pregnancy Proteins *Prolactin. Biochim Biophys Acta 1999 Oct 28;1447(2-3):291-7
PRL188 protein, Oreochromis niloticus  0   *Prolactin *Transcription Factors. FEBS Lett 1998 Oct 30;438(1-2):119-23
PRL177 protein, Oreochromis niloticus  0   *Prolactin *Transcription Factors. FEBS Lett 1998 Oct 30;438(1-2):119-23
prolactin-like protein G  0   *Pregnancy Proteins Prolactin. Biochim Biophys Acta 1998 Mar 13;1396(3):251-8
alanyl-seryl-(histidyl)6-isoleucyl-glutamyl-glycyl-arginyl-prolactin  0   *Prolactin. Biotechnol Appl Biochem 1996 Feb;23(Pt 1):67-75
Dtprp protein, rat  0   Prolactin/*analogs & derivatives. J Biol Chem 1993 Feb 15;268(5):3136-42
fluorescein-5-isothiocyanate-prolactin  0   Prolactin/*analogs & derivatives Fluorescein-5-isothiocyanate/*analogs & derivatives. Endocrinology 1991;128(4):1833
prolactin, polymeric  0   *Prolactin. J Clin Endocrinol Metab 1989;69(3):585
methionylprolactin  122463-74-5   Prolactin/*analogs & derivatives Recombinant Proteins. Mol Endocrinol 1989;3(5):822
prolactin-releasing factor (placenta)  0   *Placental Hormones Prolactin. Biochem Biophys Res Commun 1987;147(1):452
prolactin-daunomycin ligand  0   Daunorubicin/*analogs & derivatives Prolactin/*analogs & derivatives Ligands. Mol Cell Endocrinol 1986;46(3):245
prolactin, glycosylated  0   Prolactin/*analogs & derivatives. Endocrinology 1985;116(1):359
prolactin-binding protein  0   *Carrier Proteins Immunoglobulin Heavy Chains Immunoglobulin Light Chains Prolactin. Endocrinol Exp (Bratisl) 1981;15(1):55
preprolactin  65637-74-3 Prolactin, pre  *Prolactin *Protein Precursors Calmodulin-Binding Proteins. J Biol Chem 253(11):3753;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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