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Immunoglobulin Light Chains

More information in Books or onNLM PubMed
Definition: Polypeptide chains, consisting of 211 to 217 amino acid residues and having a molecular weight of approximately 22 kDa. There are two major types of light chains, kappa and lambda. Two Ig light chains and two Ig heavy chains (IMMUNOGLOBULIN HEAVY CHAINS) make one immunoglobulin molecule.  gammopathy: coordinate IMMUNOGLOBULIN LIGHT CHAINS (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA (IM), follow text; DF: IG LIGHT CHAIN   
Pharmacological Action Immunologic Factors
Examples Immunoglobulin kappa-Chains; Immunoglobulin lambda-Chains; Immunoglobulin Light Chains, Surrogate 		Other names Immunoglobulins, Light-Chain; Light-Chain, Immunoglobulin; Light Chains, Immunoglobulin; Light Chain, Immunoglobulin; Light Chain Immunoglobulins; Immunoglobulins, Light Chain; Chains, Immunoglobulin Light; Light-Chain Immunoglobulins; Immunoglobulin Light-Chain; Immunoglobulin Light Chain
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
pre-B lymphocyte protein 3, human  0   *Pre-B Cell Receptors Immunoglobulin Light Chains. Nat. Rev. Immunol. 2005; 5(7): 578-584
light chain, monoclonal antibody B23  0   *Immunoglobulin Light Chains. Gene 1996 Mar 9;169(2):237-9
immunoglobulin light chain protein Sm lambda  0   *Immunoglobulin Light Chains. Eur J Biochem 1981;115(3):643
prolactin-binding protein  0   *Carrier Proteins Immunoglobulin Heavy Chains Immunoglobulin Light Chains Prolactin. Endocrinol Exp (Bratisl) 1981;15(1):55

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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