encyclopedia of medical concepts
ψ
Phorbols
More information
in Books
or on
Definition
: The parent alcohol of the tumor promoting compounds from CROTON OIL (Croton tiglium).
carcinogens; D25-26 qualif
Examples
Phorbol Esters
Substance
CAS Registry & name
Categories
Source
Drugs
*
4alpha-
phorbol 12,13-
didecanone
0
*Phorbols.
J Invest Dermatol 2007 Mar;127(3):654-9
lactucin
0
*Lactones
*Phorbols
*Sesquiterpenes.
J Ethnopharmacol. 2006 Sep 19;107(2):254-8
pedilstatin
0
*Phorbols.
J Nat Prod 2002 Sep;65(9):1262-5
13-
O-
myristyl-
20-
O-
acetyl-
12-
deoxyphorbol
0
*Phorbols.
Fitoterapia 2001 Mar;72(3):304-6
12-
O-
acetylphorbol-
13-
decanoate
20839-15-0
*Decanoates
*Phorbols.
Chem Pharm Bull (Tokyo) 1999 Sep;47(9):1346-7
phorbol 12-
pyrenebutyrate 13-
(3,3,3-
trifloro-
2-
diazopropioate)
0
*Diazonium Compounds
*Phorbols
Isoenzymes
Protein Kinase C.
Bioorg Med Chem 1998 Jul;6(7):1117-26
pareirubrine A
147044-68-6 10H-
Azuleno(1,2,3-
ij)isoquinolin-
10-
one, 9-
hydroxy-
4,5,6,11-
tetramethoxy
*Isoquinolines
Phorbols
Tropolone/*analogs & derivatives
Alkaloids
Plant Extracts.
Chem Pharm Bull (Tokyo) 1993 Aug;41(8):1418-22
14-
deoxylactucin
74635-52-2 Azuleno(4,5-
b)furan-
2,7-
dione, 3,3a,4,5,9a,9b-
hexahydro-
4-
hydroxy-
6,9-
dimethyl-
3-
methylene-
, (3aR-
(3aalpha,4alpha,9aalpha,9bbeta))
*Lactones
*Phorbols
*Sesquiterpenes.
Planta Med 1991 Oct;57(5):444-6
xuelianlactone
107259-46-1 Azuleno(4,5-
b)furan-
2(3H)-
one, decahydro-
4-
hydroxy-
3-
methyl-
6,9-
bis(methylene)-
, (3R-
(3alpha,3abeta,4alpha,6abeta,9abeta,9balpha))
*Phorbols
*Sesquiterpenes
Drugs, Chinese Herbal.
Yao Hsueh Hsueh Pao 1986;21(9):680
phorbol
17673-25-5
*Phorbols.
J Pharm Pharmacol 1981;33(11):737
paragracine
57695-32-6
*Phorbols
*Imidazoles
Cnidarian Venoms.
Biophys J 1980;29(3):531
isohelenol
71013-32-6 Azuleno(6,5-
b)furan-
2,5-
dione, 4,4a,7a,8,9,9a-
hexahydro-
4-
hydroxy-
3-
(hydroxymethyl)-
4a,8-
dimethyl-
, (4S-
(4alpha,4abeta,7aalpha,8alpha,9aalpha))
*Phorbols
*Sesquiterpenes.
Lloydia 42(3):282;1979
isohelenalin
479-09-4 Azuleno(6,5-
b)furan-
2,5-
dione, 4,4a,7a,8,9,9a-
hexahydro-
4-
hydroxy-
3,4a,8-
trimethyl-
, (4S-
(4alpha,4abeta,7aalpha,8alpha,9aalpha))
*Phorbols
*Sesquiterpenes.
Lloydia 42(3):282;1979
tribromodamsin
67810-46-2 Azuleno(4,5-
b)furan-
2,9-
dione, 3,3,7-
tribromodecahydro
*Phorbols
*Sesquiterpenes.
Egypt J Bilharz 3(2):157;1976
solstitialin
22738-70-1 (3R-
(3 alpha,3a alpha,6a alpha,8 beta,9a alpha,9b beta))-
decahydro-
3,8-
dihydroxy-
3-
(hydroxymethyl)-
6,9-
bis(methylene)azuleno(4,5-
b)furan-
2(3H)-
one
*Phorbols
*Sesquiterpenes
Toxins, Biological.
Acta Crystallogr B 26:554;1970