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Cnidarian Venoms

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Definition: Venoms from jellyfish; CORALS; SEA ANEMONES; etc. They contain hemo-, cardio-, dermo- , and neuro-toxic substances and probably ENZYMES. They include palytoxin, sarcophine, and anthopleurine.  /antag permitted but consider also ANTIVENINS; coordinate with specific Cnidaria source   
Pharmacological Action Poisons
See Also Cnidaria; Nematocyst 		Other names Sea Anemone Venoms; Nematocyst Venoms; Jellyfish Venoms; Chironex Venoms; Venoms, Sea Anemone; Venoms, Nematocyst; Venoms, Jellyfish; Venoms, Cnidarian; Venoms, Chironex; Venom, Sea Anemone; Venom, Portuguese Man-of-War; Venom, Jellyfish; Venom, Cnidarian; Venom, Chironex; Portuguese Man of War Venom; Sea Anemone Venom; Portuguese Man-of-War Venom; Jellyfish Venom; Cnidarian Venom; Chironex Venom
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
gigantoxin-4, Stichodactyla gigantea  0   *Cnidarian Venoms. Int J Biol Sci. 2011;7(6) (dup#1):729-39
APEKTx1 peptide, Anthopleura elegantissima  0   *Cnidarian Venoms *Peptides. Biochem Pharmacol 2011 Jul 1;82(1):81-90
bunodosine 391  0   *Cnidarian Venoms. J Nat Prod. 2011 Mar 25;74(3):378-82
actinoporin RTX-A, Heteractis crispa  0   *Cnidarian Venoms. Toxicon. 2010 Apr 1;55(4):811-7
42-hydroxypalytoxin  0   *Cnidarian Venoms *Pyrans. Chem Res Toxicol 2009 Nov;22(11):1851-9
fragaceatoxin C  0   *Cnidarian Venoms. Toxicon 2009 Nov;54(6):869-80
UcI protein, Urticina crassicornis  0   *Cnidarian Venoms. Toxicon. 2009 Jun;53(7-8):762-9
toxin-2, Chironex fleckeri  0   *Cnidarian Venoms. Toxicon 2007 Nov;50(6):850-60
toxin-1, Chironex fleckeri  0   *Cnidarian Venoms. Toxicon 2007 Nov;50(6):850-60
ApC toxin  0   *Cnidarian Venoms *Peptides. Brain Res. 2006 Sep 19;1110(1):136-43
2-epi-16-deoxysarcophine  0   *Diterpenes Cnidarian Venoms. J Nat Prod 2006 Jul;69(7):1010-3
caissarolysin I, Bunodosoma caissarum  0   *Cnidarian Venoms. Biochim Biophys Acta 2006 Mar;1760(3):453-61
gigantoxin I, Stichodactyla gigantea  0   *Cnidarian Venoms *Epidermal Growth Factor. Curr Pharm Des. 2004;10(31):3885-92
APETx2 protein, Anthopleura elegantissima  0   *Cnidarian Venoms. EMBO J 2004 Apr 7;23(7):1516-25
Src1 protein, Sagartia rosea  0   *Cnidarian Venoms. Biochem Biophys Res Commun 2003 Dec 19;312(3):562-70
hydralysin  0   *Pore Forming Cytotoxic Proteins Cnidarian Venoms. Biochemistry. 2003 Aug 5;42(30):8939-44
APETx1, Anthopleura elegantissima  0   *Cnidarian Venoms. Mol Pharmacol 2003 Jul;64(1):59-69
ShK-F6CA  0   *Cnidarian Venoms *Fluoresceins. J Biol Chem 2003 Mar 14;278(11):9928-37
Chiropsalmus quadrigatus toxin-A  0   *Cnidarian Venoms. Biosci Biotechnol Biochem 2002 Jan;66(1):97-102
hemolysin CAH1  0   *Cnidarian Venoms *Hemolysin Proteins. Toxicon 2001 Jul;39(7):981-90
CRT-1 protein, Carybdea rastoni  0   *Cnidarian Venoms *Proteins. Biochem Biophys Res Commun 2000 Aug 28;275(2):582-8
magnificalysin III  0   *Peptides Cnidarian Venoms Cytotoxins Sea Anemones. Biochim Biophys Acta 2000 Mar 16;1478(1):9-18
sticholysin II  0   *Cnidarian Venoms Sea Anemones Pore Forming Cytotoxic Proteins. Protein Expr Purif 2000 Feb;18(1):71-6
HmK toxin, sea anemone  0   *Cnidarian Venoms Potassium Channels/antagonists & inhibitors. Biochemistry 1997 Sep 23;36(38):11461-71
halcurin  0   *Cnidarian Venoms Neurotoxins Sea Anemones. Toxicon 1997 Apr;35(4):537-44
AETX III toxin  0   *Cnidarian Venoms. Biochim Biophys Acta 1997 Apr 17;1335(1-2):191-8
AETX II toxin  0   *Cnidarian Venoms. Biochim Biophys Acta 1997 Apr 17;1335(1-2):191-8
AETX I toxin  0   *Cnidarian Venoms. Biochim Biophys Acta 1997 Apr 17;1335(1-2):191-8
toxin BgK  0   *Cnidarian Venoms Sea Anemones Potassium Channels/antagonists & inhibitors. J Biol Chem 1997 Feb 14;272(7):4302-9
UPI protein, sea anemone  0   *Cnidarian Venoms. Pharmacol Res 1995 Nov;32(5):309-14
coelenterolysin  0   *Cnidarian Venoms *Hemolysin Proteins. Biochem Biophys Res Commun 1995 Nov 2;216(1):348-54
kalicludine  0   *Cnidarian Venoms Neurotoxins Sea Anemones Potassium Channels/antagonists & inhibitors. J Biol Chem 1995 Oct 20;270(42):25121-6
kaliseptine  0   *Cnidarian Venoms Neurotoxins Sea Anemones Potassium Channels/antagonists & inhibitors. J Biol Chem 1995 Oct 20;270(42):25121-6
ShK neurotoxin  0   *Cnidarian Venoms Potassium Channels/antagonists & inhibitors. Toxicon 1995 May;33(5):603-13
BG III toxin  156680-12-5   *Cnidarian Venoms Sea Anemones. J Biol Chem 1994 Jun 17;269(24):16785-8
Bg II toxin  156680-13-6   *Cnidarian Venoms Sea Anemones. J Biol Chem 1994 Jun 17;269(24):16785-8
magnificalysin II  155123-76-5 Magnificalysin II  *Peptides Cnidarian Venoms Cytotoxins Sea Anemones. Toxicon 1993 Dec;31(12):1567-79
magnificalysin I  155123-75-4 Magnificalysin I  *Peptides Cnidarian Venoms Cytotoxins Sea Anemones. Toxicon 1993 Dec;31(12):1567-79
neurotoxin III, Heteractis  0   Cnidarian Venoms Neurotoxins. J Protein Chem 1993 Jun;12(3):371-8
anemone toxin BcIII (Bunodosoma caissarum)  0   *Cnidarian Venoms Neurotoxins Sea Anemones. Toxicon 1993 Jul;31(7):853-64
neurotoxin III, Radianthus macrodactylus  122781-94-6   Cnidarian Venoms Neurotoxins Sea Anemones. Bioorg Khim 1992 Sep;18(9):1164-9
Condytoxina 2  145268-54-8 Condytoxina 2  *Cnidarian Venoms Sea Anemones. Comp Biochem Physiol (C) 1992 Oct;103(2):403-9
BDS II protein, Anemonia sulcata  0   *Cnidarian Venoms. Biochem Int 1991 Jul;24(5):937-46
calitoxin  118354-83-9   *Cnidarian Venoms Neurotoxins Sea Anemones. Biochemistry 1989;28(6):2484
BDS-I antiviral protein, Anemonia sulcata  0   *Cnidarian Venoms. Biochemistry 1989;28(5):2178
neurotoxin I, Stichodactyla helianthus  117860-13-6   Cnidarian Venoms Neurotoxins. Biochemistry 1989;28(4):1820
sarcophytol B  72629-68-6 3,5,9,13-Cyclotetradecatetraene-1,2-diol, 6,10,14-trimethyl-3-(1-methylethyl)  *Diterpenes Cnidarian Venoms. J Cancer Res Clin Oncol 1989;115(1):25
sarcophytol A  72629-69-7 2,4,8,12-Cyclotetradecatetraen-1-ol, 5,9,13-trimethyl-2-(1-methylethyl)-, (S-(Z,E,E,E))  *Diterpenes Cnidarian Venoms.
Pharma Action Antineoplastic Agents 		J Cancer Res Clin Oncol 1989;115(1):25
anemone toxin BgTX8 (Bunodosoma granolifera)  0   *Cnidarian Venoms Neurotoxins Sea Anemones. Neirofiziologiia 1988;20(1):32
toxin IV (Anemonia sulcata)  0   *Cnidarian Venoms Neurotoxins Sea Anemones. Pflugers Arch 1988;411(1):88
RpIII toxin (Radianthus)  110908-25-3   *Cnidarian Venoms. FEBS Lett 1987;218(1):59
AFT-II toxin  109020-93-1   *Peptides Cnidarian Venoms Sea Anemones. Toxicon 1987;25(2):211
AFT-I toxin  109020-92-0   *Peptides Cnidarian Venoms Sea Anemones. Toxicon 1987;25(2):211
caissarone  106145-23-7 8H-Purin-8-one, 3,6,7,9-tetrahydro-3,9-dimethyl-6-(methylimino)  *Purinones Cnidarian Venoms Sea Anemones. Toxicon 1986;24(8):751
kentin  99752-37-1 Kentin  *Cnidarian Venoms Cytotoxins. Toxicon 1985;23(5):791
sea anemone toxin receptor  0   *Sodium Channels Cnidarian Venoms. Biochem Biophys Res Commun 1985;131(3):1226
variolysin  90882-02-3 Variolysin  *Cnidarian Venoms Sea Anemones. Toxicon 1984;22(2):183
cytolysin III (Stoichactis helianthus)  86179-12-6 Cytolysin III  *Cnidarian Venoms Cytotoxins Sea Anemones. J Biol Chem 1983;258(9):5574
toxin I (Anemonia sulcata)  60748-44-9   *Cnidarian Venoms Neurotoxins Sea Anemones. Pflugers Arch 1982;394(4):313
toxin V (Anemonia sulcata)  82869-85-0 Neurotoxin V  *Cnidarian Venoms Neurotoxins Sea Anemones. Biochem Biophys Res Commun 1982;107(1):272
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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