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Megestrol

More information in Books or onNLM PubMed
Definition: 17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.  a synthetic progestational hormone   
Pharmacological Action Antineoplastic Agents, Hormonal; Contraceptives, Oral, Synthetic
Examples Megestrol Acetate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
megestrol caproate  0   Megestrol/*analogs & derivatives. Bull Exp Biol Med. 2002 Jun;133(6):574-6
nomegestrol  58691-88-6 19-Norpregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl  Megestrol/*analogs & derivatives Antineoplastic Agents, Hormonal Progesterone Congeners. Rev Fr Gynecol Obstet 1985;80(10):757
nomegestrol acetate  58652-20-3   *Megestrol *Norpregnadienes Antineoplastic Agents, Hormonal Progesterone Congeners. Arzneimittelforsch 1983;33(5):710
Tri-Ervonum  67783-17-9 17-hydroxy-6-methylpregna-4,6-diene-3,20-dione, mixt. with (17 alpha)-19-norpregna-1,3,5(10)- trien-20-yne-3,17-diol  *Ethinyl Estradiol *Megestrol Contraceptives, Oral, Combined. Brux Med 54(9):511;1974; Curr Sci 47(17):614;1978
megestranol  8064-51-5   *Megestrol *Mestranol Contraceptives, Oral, Combined. Probl Endokrinol (Mosk) 191(2):87;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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