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Megestrol Acetate

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Definition: Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. It also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia. (From Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)     
Pharmacological Action Antineoplastic Agents, Hormonal; Appetite Stimulants
Other names Borea; NuMegestrol; Nu Pharm Brand of Megestrol Acetate; Nu Megestrol; LinMegestrol; Lin Megestrol; Bristol Myers Squibb Brand of Megestrol Acetate; Bristol Myers Brand of Megestrol Acetate; ApoMegestrol; Apo Megestrol; Acetate, Megestrol; Squibb Brand of Megestrol Acetate; Prasfarma Brand of Megestrol Acetate; Nu-Pharm Brand of Megestrol Acetate; Nu-Megestrol; Mestrel; Megostat; Megestat; Megefren; MegaceDrugs* : MEGACE ES; MEGACE; MEGESTROL ACETATE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PAV-M protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Doxorubicin Etoposide Megestrol Acetate. Gynecol Oncol 1995 Nov;59(2):243-8
cymegesolate  72648-88-5 pregna-4,6-dien-20-one,17-(acetyloxy)-3-(3-cyclopentyl-1-oxopropoxy)-6-methyl-, (3-beta)  *Megestrol Acetate Progesterone Congeners. Sheng Li Hsueh Pao 1985;37(4):368
Me-quingestanol  79030-51-6   *Norpregnadienes *Megestrol Acetate Contraceptives, Oral, Combined. Chung Hua Fu Chan Ko Tsa Chih 1979;14(2):68
Oraconal  8064-66-2   *Ethinyl Estradiol *Megestrol Acetate Contraceptives, Oral, Combined. Helv Chir Acta 1980;46(5-6):787; Lancet 1(8011):602;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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