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Mestranol

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Definition: The 3-methyl ether of ETHINYL ESTRADIOL. It must be demethylated to be biologically active. It is used as the estrogen component of many combination ORAL CONTRACEPTIVES.     
Pharmacological Action Estrogens 		Other names Ethinyl Estradiol 3-Methyl Ether; Ethinyl Estradiol 3 Methyl Ether
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
norbiogest  51367-42-1   *Mestranol Norethindrone/*analogs & derivatives Contraceptives, Oral, Combined. Bratisl Lek Listy 1983;80(5):603
18-methylmestranol  14009-70-2 18,19-Dinorpregna-1,3,5(10)-trien-20-yn-17-ol, 13-ethyl-3-methoxy-, (17alpha)  Mestranol/*analogs & derivatives. Yao Hsueh Hsueh Pao 14(2):70;1979
Bisecurin I  8056-92-6 19-norpregn-4-en-20-yne-3 beta,17 alpha-diol diacetate mixt. with 3-methoxy-19-norpregna-1,3,5(10) trien-20-yn-17 alpha-ol  *Ethynodiol Diacetate *Mestranol.
Pharma Action Contraceptives, Oral, Combined ; Contraceptives, Oral, Synthetic 		Am J Med 65(3):557;1978; Br J Dermatol 1982;107(2):253; Endocrinol Jpn 1979;26(5):591; Endokr Pol 23(6):533;1972; Fertil Steril 29(6):643;1978; J Clin Pathol 32(3):305;1979; Minerva Ginecol 28(7-8):664;1976; Orv Hetil 120(13):756;1979; Orv Hetil 120(2):89;1979; Orv Hetil 120(25):1525;1979; Vopr Okhr Materin Det 23(2):77;1978OVULEN-28; OVULEN; OVULEN-21
4-hydroxymestranol  0 3-methoxy-19-norpregna-1,3,5(10)-trien-20-yne- 4,17 alpha-diol  Mestranol/*analogs & derivatives. Steroids 30(3):343;1977
2-hydroxymestranol  26011-40-5 3-methoxy-19-norpregna-1,3,5(10)-trien-20-yne- 2,17 alpha-diol  Mestranol/*analogs & derivatives. Steroids 30(3):343;1977
Norinyl  8015-29-0 17-alpha-Ethynyl-19-nortestosterone and ethynylestradiol 3-methyl ether  *Mestranol *Norethindrone.
Pharma Action Contraceptives, Oral, Combined 		Int J Gynecol Obstet 14(5):385;1977; Obstet Gynecol 50(2):227;1977ORTHO-NOVUM 1/50 21; NORINYL 1+50 21-DAY; NORINYL; NORINYL 1+80 28-DAY; NORINYL 1+80 21-DAY; NORETHIN 1/50M-28; ORTHO-NOVUM 1/80 28; NORETHINDRONE AND MESTRANOL; ORTHO-NOVUM 10-21; ORTHO-NOVUM 2-21; ORTHO-NOVUM 1/50 28; NORETHIN 1/50M-21; ORTHO-NOVUM 1/80 21; NORINYL 1+50 28-DAY
sterolibrin  8077-77-8   *Mestranol Progesterone/*analogs & derivatives Contraceptives, Oral, Combined. Cesk Gynekol 40(2):89;1975; Zentralbl Gynaekol 98(3):148;1976
6-oxomestranol-6-(O-carboxymethyl)oxime  0   Mestranol/*analogs & derivatives. Steroids 22(3):327;1973
Infecundin  8015-30-3 17 alpha-hydroxy-19-norpregn-5(10)-en-20-yn-3- one mixt. with (17 alpha)-3-methoxy-19-norpregna- 1,3,5(10)-trien-20-yn-17-ol  *Mestranol *Norethynodrel.
Pharma Action Contraceptive Agents, Female ; Estrogens ; Progestins 		Akush Ginekol (5):35;1979; Akush Ginekol (Mosk) (7):48;1; Akush Ginekol (Mosk) 1979;10:41; Akush Ginekol 12:52;1975; Akush Ginekol 2:55;1979; Akush Ginekol 7:35;1977; Akush Ginekol 7:48-61;1976; Akush Ginekol 8:40;1978; Akush Ginekol 9:29;1977; Cancer Res 38(11):4053;1978; Farmakol Toksikol 42(4):426;1979; Fertil Steril 29(6):643;1978; Harefuah 81(10):500;1971; Orv Hetil 115(16):924;1974; Orv Hetil 120(13):756;1979; Sov Med (6):76;1979; Sov Med 1979;(7):78; Vestn Dermatol Venerol 2:18;1977ENOVID-E; ENOVID; ENOVID-E 21
megestranol  8064-51-5   *Megestrol *Mestranol Contraceptives, Oral, Combined. Probl Endokrinol (Mosk) 191(2):87;1973
Ovosiston  8065-91-6   *Chlormadinone Acetate *Mestranol Contraceptives, Oral, Combined. Pol Tyg Lek 1979;34(49):1923
Noracycline  8015-14-3   *Lynestrenol *Mestranol.
Pharma Action Contraceptives, Oral, Combined 		J Steroid Biochem 9(8):811;1978
BDH 2398  974-76-5 19-norpregna-1,3,5(10)-trien-20-yn-17-ol, 21-chloro-3-methoxy-, (17 alpha)  Mestranol/*analogs & derivatives.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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