|
| The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990)
| /biosyn /physiol permitted; DF: note short X ref
| Other names LTB4; 5,12-diHETE; 5,12-HETE; Leukotriene B 4; B-4, Leukotriene; 5,12 diHETE; 5,12 HETE; Leukotrienes B; Leukotriene B-4; Leukotriene B; LTB4; 5,12-diHETE; 5,12-HETE
| |
| Substance | CAS Registry & name | Categories | Source | Drugs*
|
| leukotriene B5
| 80445-66-5
|
Leukotriene B4/*analogs & derivatives Eicosapentaenoic Acid/*analogs & derivatives.
|
Biochem Biophys Res Commun 1983;117(1):282
|
5,12,20-trihydroxy-6,8,10,14-eicosatetraenoic acid
79008-24-5
6,8,10,14-Eicosatetraenoic acid, 5,12,20-trihydroxy-, (S-(R*,R*-(E,E,Z,Z)))
|
Leukotriene B4/*analogs & derivatives.
|
FEBS Lett 1981;128(2):329
|
| LTB4R protein, human
| 0
|
Leukotriene B4 *Receptors, Leukotriene B4.
|
|
8,15-leukotriene B4
77667-08-4
5,9,11,13-Eicosatetraenoic acid, 8,15-dihydroxy
|
Leukotriene B4/*analogs & derivatives.
|
Biochem Biophys Res Commun 1981;99(3):976
|
| LTB4R2 protein, human
| 0
|
Leukotriene B4 *Receptors, Leukotriene B4.
|
|
14,15-leukotriene B4
77667-09-5
5,8,10,12-Eicosatetraenoic acid, 14,15-dihydroxy
|
Leukotriene B4/*analogs & derivatives.
|
Biochem Biophys Res Commun 1981;99(3):976
|
| leukotriene B3
| 88099-35-8
|
Leukotriene B4/*analogs & derivatives.
|
Arch Pharm (Weinheim) 1985;318(3):225
|
20-carboxy-leukotriene B4
| 83861-61-4
|
Leukotriene B4/*analogs & derivatives.
|
Biochem Biophys Res Commun 1985;132(3):864
|
| hinokiresinol
| 17676-24-3
|
*Phenols *Lignans Leukotriene B4/antagonists & inhibitors.
|
Planta Med 1999 May;65(4):391-2
|
| Ltb4r2 protein, mouse
| 0
|
Leukotriene B4 *Receptors, Leukotriene B4.
|
J Biol Chem 2000 Sep 1;275(35):27000-4; J Exp Med 2000 Aug 7;192(3):421-32
|
5,12-dihydroxy-6,8,14-eicosatrienoic acid
| 120904-46-3
|
Leukotriene B4/*analogs & derivatives.
|
Biochem Biophys Res Commun 1990;170(1):23
|
DPC11870-11
| 0
|
Leukotriene B4/antagonists & inhibitors *Biphenyl Compounds *Oligopeptides *Pyridines *Tetrazoles.
|
J Nucl Med 2003 Jul;44(7);1087-91
|
| leukotriene B4 dimethylamide
| 83024-92-4
6,8,10,14-Eicosatetraenamide, 5,12-dihydroxy-N,N-dimethyl-, (S-(R*,S*-(E,Z,E,Z)))
|
Leukotriene B4/*analogs & derivatives.
|
Biochem Biophys Res Commun 1982;106(3):741
|
20-aldehyde leukotriene B4
| 115609-68-2
|
Leukotriene B4/*analogs & derivatives.
|
J Biol Chem 1988;263(17):7996
|
20-trifluoromethylleukotriene B4
115178-97-7
6,8,10,14-Eicosatetraenoic acid, 20,20,20-trifluoro-5,12-dihydroxy-, (S-(R*,S*-(E,Z,E,Z)))
|
Leukotriene B4/*analogs & derivatives.
|
Prostaglandins 1989;37(2):287
|
12-oxoleukotriene B4
136696-10-1
6,8,10,14-Eicosatetraenoic acid, 5-hydroxy-12-oxo-, (S-(E,Z,E,Z))
|
Leukotriene B4/*analogs & derivatives.
|
J Biol Chem 1993 Aug 25;268(24):18128-35
|
3-hydroxyleukotriene B4
| 0
|
Leukotriene B4/*analogs & derivatives.
|
J Pharmacol Exp Ther 1994 Dec;271(3):1514-9
|
| A 93176
| 0
|
*Quinolines Leukotriene B4/antagonists & inhibitors Stereoisomerism.
|
Adv Exp Med Biol 1997;433:91-4
|
18-carboxy-19,20-dinorleukotriene B4
| 102674-12-4
|
Leukotriene B4/*analogs & derivatives.
|
J Biol Chem 1986;261(12):5414
|
5,12,19-trihydroxy-6,8,10,14-eicosatetraenoic acid
| 117605-61-5
|
Leukotriene B4/*analogs & derivatives.
|
Biochem Biophys Res Commun 1989;159(3):1283
|
12-methylleukotriene B3
| 148504-32-9
|
Leukotriene B4/*analogs & derivatives.
|
Prostaglandins 1993 Apr;45(4):335-45
|
| SC 45694
| 120772-66-9
6-Heptenoic acid, 5-hydroxy-7-(4-(1-hydroxy-3-nonenyl)phenyl)-, monolithium salt
|
Leukotriene B4/*analogs & derivatives.
|
J Pharmacol Exp Ther 1994 Mar;268(3):1493-8
|
| obtusatic acid
| 0
|
Leukotriene B4/antagonists & inhibitors *Benzoates.
|
Eur J Med Chem 2000 Apr;35(4):405-11
|
| leukotriene B4 glucuronide
| 0
|
*Glucuronides Leukotriene B4/*analogs & derivatives.
|
Clin Exp Allergy 2004 Aug;34(8):1262-9
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