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Keratoderma, Palmoplantar

More information in Books or onNLM PubMed
Definition: Group of mostly hereditary disorders characterized by thickening of the palms and soles as a result of excessive keratin formation leading to hypertrophy of the stratum corneum (hyperkeratosis).  KERATODERMA, PALMOPLANTAR, DIFFUSE is also available; do not confuse entry term HYPERKERATOSIS PALMARIS ET PLANTARIS with POROKERATOSIS PALMARIS ET PLANTARIS DISSEMINATA see POROKERATOSIS   
See Also Erythrokeratodermia Variabilis
Examples Keratoderma, Palmoplantar, Diffuse; Papillon-Lefevre Disease
Other names Palmoplantar Keratoderma; Meleda Disease; Keratosis, Palmoplantar; Keratosis Palmaris et Plantaris; Hyperkeratosis Palmaris et Plantaris; de Meleda, Mal; Palmoplantar Keratosis; Palmoplantar Keratoses; Palmoplantar Keratodermas; Meleda, Mal de; Keratoses, Palmoplantar; Keratodermas, Palmoplantar; Disease, Meleda; Mal de Meleda; Keratosis Palmoplantaris Transgradiens of Siemens
 
SubstanceCAS Registry & nameCategoriesSource
Powell Venencie Gordon syndrome  0   *Keratoderma, Palmoplantar *Muscle Spasticity.
Naxos disease  0   *Hair Diseases *Keratoderma, Palmoplantar *Arrhythmogenic Right Ventricular Dysplasia.
Naegeli syndrome  0   *Ectodermal Dysplasia *Hypohidrosis *Keratoderma, Palmoplantar.
Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome  0   *Keratoderma, Palmoplantar *Neurocutaneous Syndromes.
Judge Misch Wright syndrome  0   *Corneal Dystrophies, Hereditary *Facial Dermatoses *Keratoderma, Palmoplantar *Nail Diseases.
Basaran Yilmaz syndrome  0   *Hypotrichosis *Keratoderma, Palmoplantar *Nail Diseases *Pigmentation Disorders.
Stern Lubinsky Durrie syndrome  0   *Corneal Diseases *Growth Disorders *Keratoderma, Palmoplantar *Limb Deformities, Congenital Infant, Premature.
Knuckle pads, leuconychia and sensorineural deafness  0   *Abnormalities, Multiple *Hearing Loss, Sensorineural *Keratoderma, Palmoplantar.
Fitzsimmons-McLachlan-Gilbert syndrome  0   *Keratoderma, Palmoplantar *Intellectual Disability *Spastic Paraplegia, Hereditary.
Alopecia congenita keratosis palmoplantaris  0   *Alopecia/congenital *Keratoderma, Palmoplantar.
Tyrosine transaminase deficiency  0   *Corneal Diseases *Keratoderma, Palmoplantar *Tyrosinemias.
Vohwinkel syndrome  0   *Abnormalities, Multiple *Hand Deformities, Congenital *Hearing Loss, Sensorineural *Keratoderma, Palmoplantar.
Corneodermatoosseous syndrome  0   *Corneal Dystrophies, Hereditary *Keratoderma, Palmoplantar *Lower Extremity Deformities, Congenital.
Porokeratosis punctata palmaris et plantaris  0   *Keratoderma, Palmoplantar *Porokeratosis. Arch. Derm. 1971;104: 682
Patel Bixler syndrome  0   *Alopecia *Keratoderma, Palmoplantar *Nail Diseases.
Keratosis palmoplantaris with esophageal cancer  0   *Esophageal Neoplasms *Keratoderma, Palmoplantar.
Keratosis palmoplantaris striata 3  0   *Keratoderma, Palmoplantar.
Keratosis palmoplantaris striata 1  0   *Keratoderma, Palmoplantar.
Keratosis palmoplantaris papulosa  0   *Keratoderma, Palmoplantar.
Keratosis focal palmoplantar gingival  0   *Gingival Diseases *Keratoderma, Palmoplantar.
Keratoderma palmoplantar spastic paralysis  0   *Charcot-Marie-Tooth Disease *Keratoderma, Palmoplantar *Nail Diseases.
Keratoderma palmoplantar deafness  0   *Hearing Loss, Sensorineural *Keratoderma, Palmoplantar.
Acrokeratoelastoidosis of Costa  0   *Keratoderma, Palmoplantar.
Cardiomyopathy dilated with Woolly hair and keratoderma  0   *Hair Diseases *Keratoderma, Palmoplantar *Cardiomyopathies.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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