Histamine H2 Antagonists (definition)

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ψ ψ	Histamine H2 Antagonists

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Definition: Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.

GEN or unspecified; prefer specifics; DF: HISTAMINE H2 ANTAG
See Also Anti-Ulcer Agents

Other names Histamine H2 Receptor Blockaders; Histamine H2 Receptor Antagonists; Antihistaminics, H2; H2 Blockers, Histamine; H2 Antihistaminics; H2 Antagonists, Histamine; Blockers, Histamine H2; Blockaders, H2 Receptor; Receptor Blockaders, H2; Receptor Antagonists, Histamine H2; Histamine H2 Blockers; H2 Receptor Blockaders; Blockaders, Histamine H2 Receptor; Antagonists, Histamine H2

Substances having this pharmacologic action: tiotidine; oxmetidine; SK&F 93479; etintidine; mifentidine; loxtidine; lafutidine; Nizatidine; Cimetidine; Ranitidine; Famotidine; Metiamide; Burimamide; ranitidine bismuth citrate; ebrotidine; roxatidine acetate; zolantidine; TZU 0460

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor

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