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Bacterial Toxins

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Definition: Toxic substances formed in or elaborated by bacteria; they are usually proteins with high molecular weight and antigenicity; some are used as antibiotics and some to skin test for the presence of or susceptibility to certain diseases.  GEN or unspecified: prefer specifics; coord IM with specific bacterium (IM); /antag permitted but consider also ANTITOXINS; DF: BACT TOXINS   
Examples Botulinum Toxins; Cholera Toxin; Cord Factors; Diphtheria Toxin; Endotoxins; Exfoliatins; Shiga Toxins; Streptolysins; Tetanus Toxin; Virulence Factors, Bordetella 		Other names Toxins, Bacterial
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
BPSL1549 protein, Burkholderia pseudomallei  0   *Bacterial Proteins *Bacterial Toxins Cytotoxins Eukaryotic Initiation Factor-4A/antagonists & inhibitors. Science. 2011 Nov 11;334(6057):821-4
tosA protein, E coli  0   *Bacterial Toxins *Escherichia coli Proteins. MBio. 2011;2(3) (dup#1):e00066-11
YfjG protein, E coli  0   *Bacterial Toxins *Escherichia coli Proteins. Mol Microbiol 2011 Mar;79(6):1418-29
YeeV protein, E coli  0   *Bacterial Toxins *Escherichia coli Proteins. Mol Microbiol 2011 Jan;79(1):109-18
IbsC protein, E coli  0   *Bacterial Toxins *Escherichia coli Proteins. J Biol Chem 2010 Dec 31;285(53):41627-36
toxin R, Clostridium difficile  0   *Bacterial Toxins. Med Sci (Paris). 2010 Feb;26(2):153-8
CARDS toxin, Mycoplasma pneumoniae  0   *Bacterial Proteins *Bacterial Toxins. PLoS One 2009;4(10):e7562
amylosin, Bacillus  0   *Bacterial Toxins. J Appl Microbiol. 2009 Jun;106(6):1976-85
YafO protein, E coli  0   *Bacterial Toxins *Escherichia coli Proteins. J Biol Chem 2009 Sep 18;284(38):25522-31
HigB protein, Proteus vulgaris  0   *Bacterial Proteins Bacterial Toxins. J Biol Chem. 2009 Jul 10;284(28):18605-13
vaginolysin, Gardnerella vaginalis  0   *Bacterial Proteins *Bacterial Toxins. J Bacteriol. 2008 Jun;190(11):3896-903
immunotoxin HA22  0   *Bacterial Toxins *Exotoxins. Clin Cancer Res 2009 Feb 1;15(3):832-9
NetB protein, Clostridium perfringens  0   *Bacterial Toxins *Enterotoxins. PLoS Pathog 2008 Feb 8;4(2):e26
Pet protein, E coli  EC 3.4.21.-   *Bacterial Toxins *Enterotoxins *Serine Endopeptidases *Escherichia coli Proteins.
cholix toxin, Vibrio cholerae  EC 3.6.5.2   *Bacterial Toxins *ADP-Ribosylation Factors. J Biol Chem 2008 Apr 18;283(16):10671-8
parasporin-2Ab protein, Bacillus thuringiensis  0   *Bacterial Toxins. Curr Microbiol 2007 Oct;55(4):278-83
yhaV protein, E coli  0   *Bacterial Toxins *Escherichia coli Proteins. J Mol Biol 2007 Sep 28;372(4):894-905
prlF protein, E coli  0   *Bacterial Toxins *Escherichia coli Proteins. J Mol Biol 2007 Sep 28;372(4):894-905
microcystin-LF  0   *Microcystins Bacterial Toxins. Environ Toxicol 2007 Aug;22(4):436-42
homoanatoxin-a  0   *Bacterial Toxins *Bicyclo Compounds, Heterocyclic. Toxicon 2003 Oct;42(5):533-8
YafQ protein, E coli  0   *Bacterial Toxins *Escherichia coli Proteins. FEMS Microbiol Lett 2007 Mar;268(1):112-9
alpha-xenorhabdolysin, Xenorhabdus nematophila  0   *Bacterial Proteins *Bacterial Toxins. J Biol Chem 2007 Mar 30;282(13):9571-80
PRX302  0   *Bacterial Toxins *Pore Forming Cytotoxic Proteins. J Natl Cancer Inst 2007 Mar 7;99(5):376-85
mitilysin, Streptococcus mitis  0   *Bacterial Toxins. J Bacteriol 2007 Jan;189(2):627-32
mycolactone F  0   *Fatty Acids, Unsaturated *Lactones Bacterial Toxins. Infect Immun 2006 Nov;74(11):6037-45
seeligeriolysin O, Listeria seeligeri  0   *Bacterial Toxins. Int Immunol 2005 Dec;17(12):1597-606
p29 crystal protein, Bacillus thuringiensis  0   *Bacterial Proteins *Bacterial Toxins. Biosci Biotechnol Biochem. 2005 Nov;69(11):2063-72
secreted autotransporter toxin, E coli  0   *Bacterial Toxins *Escherichia coli Proteins. FEMS Microbiol Lett 2005 Sep 15;250(2):263-9
YoeB protein, E coli  0   *Bacterial Toxins *Escherichia coli Proteins. J Biol Chem 2005 Aug 26;280(34):30063-72
Hlg2 protein, Staphylococcus  0   *Bacterial Proteins *Bacterial Toxins *Hemolysin Proteins. J Biochem (Tokyo) 2004 Oct;136(4):427-31
pinnamine  0   *Bacterial Toxins. J Org Chem. 2005 Jul 8;70(14):5688-97
McyH protein, Microcystis aeruginosa  0   *Bacterial Toxins *ATP-Binding Cassette Transporters. Appl Environ Microbiol 2004 Nov;70(11):6370-8
Clostridium difficile lethal toxin B  0   *Bacterial Toxins. Circulation 2004 Apr 13;109(14):1795-801
immunotoxin 4D5MOCB-ETA  0   *Bacterial Toxins *Immunoglobulin Fragments. Clin Cancer Res 2003 Jul;9(7);2837-48
4-hydroxyhomoanatoxin-a  0   *Bacterial Toxins *Marine Toxins. Toxicon. 2003 Oct;42(5):533-8
interleukin-4-Pseudomonas exotoxin  0   *Bacterial Toxins *Exotoxins *Interleukin-4. J Neurooncol 2003 Aug-Sep;64(1-2):125-37
ExoT protein, Pseudomonas aeruginosa  0   *GTPase-Activating Proteins *ADP Ribose Transferases Bacterial Toxins. J Biol Chem 2003 Aug 29;278(35):32794-800
HEC toxin, Aeromonas hydrophila  0   *Bacterial Toxins. Wei Sheng Wu Xue Bao 1992 Dec;32(6):432-8.
fst toxin, Enterococcus faecalis  0   *Bacterial Toxins. Mol Microbiol 2001 Oct;42(2):527-37
CdtC protein, Haemophilus ducreyi  0   *Bacterial Toxins Protein Subunits. Microb Pathog 2002 Aug;33(2):49-62
CdtA protein, Haemophilus ducreyi  0   *Bacterial Toxins Protein Subunits. Microb Pathog 2002 Aug;33(2):49-62
ChpAK protein, E coli  0   *Bacterial Toxins *Escherichia coli Proteins. J Bacteriol 1993 Nov;175(21):6850-6
RelE protein, E coli  0   *Bacterial Toxins *Escherichia coli Proteins. Mol Microbiol 1998 Aug;29(4):1065-76
LdrD protein, E coli  0   *Bacterial Toxins *Escherichia coli Proteins. Mol Microbiol 2002 Jul;45(2):333-49
syringopeptin SP(22)Phv  0   *Peptides, Cyclic Bacterial Toxins. Biochim Biophys Acta 2002 May 20;1597(1):81-9
cytolethal distending toxin, Actinobacillus actinomycetemcomitans  0   *Bacterial Toxins Protein Subunits. Infect Immun 1998 Oct;66(10):5008-19
exoenzyme S  EC 2.4.2.31   *Bacterial Toxins *ADP Ribose Transferases Cytotoxins.
ChpK protein, bacteria  0   *Bacterial Toxins. J Bacteriol 2001 Nov;183(21):6494-7
RtxC protein, Vibrio cholerae  EC 2.3.-   *Acyltransferases *Bacterial Proteins Bacterial Toxins. J Clin Microbiol 2001 Jul;39(7):2594-7
RtxA protein, Vibrio cholerae  0   *Bacterial Toxins. J Clin Microbiol 2001 Jul;39(7):2594-7
XptA1 protein, Xenorhabdus nematophilus  0   *Bacterial Proteins *Bacterial Toxins. Appl Environ Microbiol 2001 May;67(5):2062-9
Vibrio cholerae WO7 toxin  0   *Bacterial Toxins. Microbiol Immunol 2000;44(11):931-40
SepC protein, Serratia entomophila  0   *Bacterial Toxins. J Bacteriol 2000 Sep;182(18):5127-38
SepB protein, Serratia entomophila  0   *Bacterial Toxins. J Bacteriol 2000 Sep;182(18):5127-38
sepA protein, Serratia entomophila  0   *Bacterial Proteins *Bacterial Toxins. J Bacteriol 2000 Sep;182(18):5127-38
cell-elongating factor, Vibrio cholerae  0   *Bacterial Toxins Vibrio cholerae. Microb Pathog 2000 Jul;29(1):1-8
CRY1BD protein, Bacillus thuringiensis  0   *Bacterial Proteins *Bacterial Toxins. Curr Microbiol 2000 Apr;40(4): 227-32
CRY1GB protein, Bacillus thuringiensis  0   *Bacterial Proteins *Bacterial Toxins. Curr Microbiol 2000 Apr;40(4): 227-32
lymphostatin protein, E coli  0   *Bacterial Toxins *Escherichia coli Proteins. Infect Immun 2000 Apr;68(4):2148-55
Bacillus sphaericus binary toxin receptor  0   *Receptors, Cell Surface alpha-Glucosidases Bacterial Toxins. Insect Biochem Mol Biol 1999 Aug;29(8):711-21
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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