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Cord Factors

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Definition: Toxic glycolipids composed of trehalose dimycolate derivatives. They are produced by MYCOBACTERIUM TUBERCULOSIS and other species of MYCOBACTERIUM. They induce cellular dysfunction in animals.     
Pharmacological Action Adjuvants, Immunologic 		Other names Trehalose Dimycolates; Trehalose 6,6' Dimycolate; Factors, Cord; Factor, Cord; Dimycolates, Trehalose; Trehalose-6,6'-Dimycolate; Cord Factor
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Ribi adjuvant  0   *Cord Factors *Cell Wall Skeleton Lipid A/*analogs & derivatives Adjuvants, Immunologic. J Immunol Methods 1992 Jul 31;152(1):105-13
6,6'-di-O-mycoloyltrehalose  0   *Cord Factors. Carbohydr Res 1991;212:47
6-deoxy-6-mycoloylamino-alpha,alpha-trehalose  0   *Cord Factors. Carbohydr Res 1989;194:199
6-O-corynomycoloyltrehalose  68681-65-2   *Cord Factors. Carbohydr Res 1986;155:229
6-O-mycoloyltrehalose  0   *Cord Factors. Carbohydr Res 1986;155:229
6,6'-dicorynomycolyl trehalose  93379-98-7 beta-D-Glucopyranoside, 6-O-(3-hydroxy-1-oxo-2-tetradecyloctadecyl)-beta-D-glucopyranosyl, (3aS-(3aalpha,4beta,6aalpha))  *Cord Factors. Ann Microbiol (Paris) 1984;135B(1):13
6,6'-di-O-corynomycolyl galactopyranosyl-galactopyranoside  93602-72-3 alpha-D-Galactopyranoside, 6-O-(3-hydroxy-1-oxo-2-tetradecyloctadecyl)-alpha-D-galactopyranosyl, (3alpha,5beta,7alpha,12alpha,24xi)  *Cord Factors. Carbohydr Res 1984;133(1):53
6,6'-di-O-mycolyl galactopyranosyl-galactopyranoside  0   *Cord Factors. Carbohydr Res 1984;133(1):53
SS 554  84396-34-9 alpha-D-Glucopyranoside, 6-O-(1-oxodecyl)-alpha-D-glucopyranosyl, 6-decanoate  Trehalose/*analogs & derivatives Cord Factors. Gan To Kagaku Ryoho 1984;11(8):1629
trehalose monomycolate  0   *Cord Factors. Antimicrob Agents Chemother 16(2):240;1979
corynomycoloyl-D-trehalose  0   *Cord Factors. Biomed Mass Spec 5(2):146;1978
6-mycolyl-6'-acetyltrehalose  0   *Cord Factors. Biochemistry 15(2):441;1976; J Bacteriol 130(1):569;1977

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