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Interleukin-4

More information in Books or onNLM PubMed
Definition: A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells.  DF: IL 4 or IL4   
Pharmacological Action Adjuvants, Immunologic; Antineoplastic Agents; Antirheumatic Agents
See Also Histocompatibility Antigens Class II
Other names B-Cell Growth Factor-I; Mast Cell Growth Factor-2; IL-4; Binetrakin; B-Cell Stimulatory Factor-1; Mast Cell Growth Factor 2; Interleukin 4; B Cell Stimulatory Factor 1; B Cell Stimulating Factor 1; B Cell Proliferating Factor; B Cell Growth Factor I; B Cell Growth Factor 1; MCGF-2; BSF-1; BCGF-1; B-Cell Stimulatory Factor 1; B-Cell Stimulating Factor-1; B-Cell Proliferating Factor; B-Cell Growth Factor-1; B Cell Stimulatory Factor-1
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
pitrakinra  0   *Interleukin-4 Interleukin-4/antagonists & inhibitors Interleukin-13/antagonists & inhibitors. Lancet 2007 Oct 20;370(9596):1422-31
IL4 protein, human  0   *Interleukin-4.
interleukin-4-Pseudomonas exotoxin  0   *Bacterial Toxins *Exotoxins *Interleukin-4. J Neurooncol 2003 Aug-Sep;64(1-2):125-37
deacetylravidomycin M  0   *Aminoglycosides Interleukin-4/antagonists & inhibitors. J Antibiot (Tokyo) 2001 Jul;54(7):554-61
interleukin-4 variant  0   *Interleukin-4. Blood 2001 Feb 1;97(3):752-8
interleukin 4 (38-37)-PE38KDEL  0   Interleukin-4 Immunotoxins. Nat Med 1999 Jul;5(7):817-22
interleukin 4 (1-129)-PE38KDEL  0   *Interleukin-4 Immunotoxins. Mat Med 1999 Jul;5(7):738-9
DAB(389)-interleukin 4  0   *Diphtheria Toxin *Interleukin-4 Recombinant Fusion Proteins Immunotoxins. J Allergy Clin Immunol 1995 Apr;95(4):893-900
diphtheria toxin-related-murine interleukin-4-fusion toxin  0   *Diphtheria Toxin *Interleukin-4 Recombinant Fusion Proteins. Protein Eng 1992 Apr;5(3):241-8
IL-4-PE40 protein, recombinant  0   *Exotoxins *Recombinant Fusion Proteins *Interleukin-4 Bacterial Proteins. Proc Natl Acad Sci USA 1989;86(11):4215

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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