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Forkhead Transcription Factors

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Definition: A subclass of winged helix DNA-binding proteins that share homology with their founding member fork head protein, Drosophila.     
Examples Hepatocyte Nuclear Factor 3-alpha; Hepatocyte Nuclear Factor 3-beta; Hepatocyte Nuclear Factor 3-gamma 		Other names Transcription Factors, Fox; Transcription Factors, Forkhead; Fox Transcription Factors; Forkhead Proteins; Forkhead Box Transcription Factors; Forkhead Box Proteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Foxo6 protein, rat  0   *Forkhead Transcription Factors. Genes Dev 2010 Apr 15;24(8):799-813
FoxP1 protein, rat  0   *Repressor Proteins *Forkhead Transcription Factors. Mol Cell Biol 2011 Jul;31(14):3068-80
Foxp2 protein, rat  0   *Forkhead Transcription Factors. J Neurosci Res 2003 Jul 1;73(1):61-72
CG12632 protein, Drosophila  0   *Drosophila Proteins *Forkhead Transcription Factors. PLoS Biol 2011;9(1):e1000568
Foxp3 protein, zebrafish  0   *Zebrafish Proteins *Forkhead Transcription Factors. PLoS One 2010;5(3):e9478
Foxn3 protein, mouse  0   *Forkhead Transcription Factors. Biochem Biophys Res Commun 2010 Sep 10;400(1):60-5
Foxf2 protein, Xenopus  0   *Xenopus Proteins *Forkhead Transcription Factors. Int J Dev Biol 2010;54(5):919-24
Foxi3 protein, zebrafish  0   *Zebrafish Proteins *Forkhead Transcription Factors. Int J Dev Biol 2010;54(5):837-50
FoxQ1 protein, zebrafish  0   *Zebrafish Proteins *Forkhead Transcription Factors. Chem Res Toxicol 2010 Mar 15;23(3):480-7
FOXO3a protein, C elegans  0   *Caenorhabditis elegans Proteins *Forkhead Transcription Factors. Aging Cell. 2009 Dec;8(6):690-705
Foxd5 protein, zebrafish  0   *Zebrafish Proteins *Forkhead Transcription Factors. Dev Biol 2009 Dec 15;336(2):232-45
Foxl2 protein, Xenopus  0   *Xenopus Proteins *Forkhead Transcription Factors. Sex Dev 2009;3(1):38-42
Foxg1 protein, zebrafish  0   *Zebrafish Proteins *Forkhead Transcription Factors. J Neurosci 2008 May 14;28(20):5229-39
Foxj1.2 protein, zebrafish  0   *Zebrafish Proteins *Forkhead Transcription Factors. Int J Dev Biol 2008;52(7):985-91
FoxK protein, Drosophila  0   *Drosophila Proteins *Forkhead Transcription Factors. J Cell Biol 2008 Dec 15;183(6):1049-60
Foxj1 protein, zebrafish  0   *Forkhead Transcription Factors. Nat Genet 2008 Dec;40(12):1445-53
Foxn4 protein, zebrafish  0   *Zebrafish Proteins *Forkhead Transcription Factors. Genes Dev 2008 Mar 15;22(6):734-9
FoxF2 protein, rat  0   *Forkhead Transcription Factors. Circ Res 2008 Feb 1;102(2):e20-35
FoxE1 protein, rat  0   *Forkhead Transcription Factors. Mol Cell Biol 2007 Oct;27(20):7302-14
FoxO6protein, mouse  0   *Forkhead Transcription Factors. J Biol Chem 2003 Sep 19;278(38):35959-67
FoxO4 protein, mouse  0   *Forkhead Transcription Factors. Mamm Genome 2001 Jun;12(6):416-25
FOXO4 protein, rat  0   *Forkhead Transcription Factors. Kidney Int 2007 Oct;72(8):965-76
FoxN3 protein, Xenopus  0   *Xenopus Proteins *Forkhead Transcription Factors. Dev Dyn 2007 Jan;236(1):226-39
FOXN4 protein, Xenopus  0   *Xenopus Proteins *Forkhead Transcription Factors Eye Proteins Nerve Tissue Proteins. Gene Expr Patterns 2007 Jan;7(3):233-8
foxe3 protein, zebrafish  0   *Eye Proteins *Zebrafish Proteins *Forkhead Transcription Factors. Mech Dev. 2006 Oct;123(10):761-82
Foxl1 protein, zebrafish  0   *Zebrafish Proteins *Forkhead Transcription Factors. Mol Cell Biol 2006 Oct;26(19):7246-57
Foxm1 protein, rat  0   *Forkhead Transcription Factors.
fkh protein, Drosophila  0   *Nuclear Proteins *Transcription Factors Forkhead Transcription Factors.
FOXH1 protein, human  0   *Forkhead Transcription Factors Signal Transduction.
mde2 protein, S. pombe  0   *Schizosaccharomyces pombe Proteins *Forkhead Transcription Factors. Curr Biol. 2005 Sep 20;15(18):1663-9
Foxi1 protein, mouse  0   *Forkhead Transcription Factors. Biochem J 2006 Jan 1;393(Pt 1):277-83
FoxE1 protein, Xenopus  0   *Xenopus Proteins *Forkhead Transcription Factors. Int J Dev Biol 2005;49(7):881-4
FoxO3 protein, Xenopus  0   *Xenopus Proteins *Forkhead Transcription Factors. Gene Expr Patterns 2004 Dec;5(2):187-92
FoxO1 protein, Xenopus  0   *Xenopus Proteins *Forkhead Transcription Factors. Gene Expr Patterns 2004 Dec;5(2):187-92
FoxP2 protein, zebrafish  0   *Zebrafish Proteins *Forkhead Transcription Factors Nerve Tissue Proteins Zinc Fingers. Dev Dyn 2005 Nov;234(3):740-6
FoxM1 protein, Xenopus  0   *Xenopus Proteins *Forkhead Transcription Factors. Int J Dev Biol 2005;49(1):53-8
FOXD3 protein, human  0   *Forkhead Transcription Factors Trans-Activators Helix-Turn-Helix Motifs. J Invest Dermatol 2005 Aug;125(2):388-91
Xema protein, Xenopus  0   *Xenopus Proteins *Forkhead Transcription Factors DNA-Binding Proteins. Development 2005 Jun;132(12):2733-42
FOXD1 protein, human  0   *Forkhead Transcription Factors. J Biol Chem 1996 Aug 30;271(35):21094-9
FOXN4 protein, human  0   *Forkhead Transcription Factors. Int J Mol Med 2004 Nov;14(5):949-53
FOXJ1 protein, rat  0   *Forkhead Transcription Factors. J Mol Endocrinol 2004 Jun;32(3):615-25
Fhl1 protein, S pombe  0   *Schizosaccharomyces pombe Proteins *Forkhead Transcription Factors. Gene 2005 Mar 28;348:101-9
Foxp3 protein, rat  0   *Forkhead Transcription Factors. Transpl Immunol 2004 Dec;13(4):239-47
Foxn6 protein, rat  0   *Forkhead Transcription Factors. Int J Oncol. 2004 Jul;25(1):219-23
Foxr2 protein, mouse  0   *Forkhead Transcription Factors. Int J Oncol. 2004 Jul;25(1):219-23
FOXR2 protein, human  0   *Forkhead Transcription Factors. Int J Oncol. 2004 Jul;25(1):219-23
FOXO3 protein, human  0   *Forkhead Transcription Factors.
Foxo3a protein, rat  0   *Forkhead Transcription Factors.
Foxo1a protein, rat  0   *Forkhead Transcription Factors.
FOXO1A protein, pig  0   *Forkhead Transcription Factors.
Foxl2 protein, mouse  0   *Forkhead Transcription Factors.
Foxp3 protein, mouse  0   *Forkhead Transcription Factors.
Foxe3 protein, mouse  0   *Forkhead Transcription Factors.
let-381 protein, C elegans  0   *Caenorhabditis elegans Proteins *Forkhead Transcription Factors.
lens1 protein, Xenopus  0   *Xenopus Proteins *Forkhead Transcription Factors.
Foxk1 protein, mouse  0   *Forkhead Transcription Factors.
fkh-9 protein, C elegans  0   *Caenorhabditis elegans Proteins *Forkhead Transcription Factors.
fkh-8 protein, C elegans  0   *Caenorhabditis elegans Proteins *Forkhead Transcription Factors.
fkh-6 protein, C elegans  0   *Caenorhabditis elegans Proteins *Forkhead Transcription Factors.
fkh-10 protein, C elegans  0   *Caenorhabditis elegans Proteins *Forkhead Transcription Factors.
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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