encyclopedia of medical concepts
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Cyclooxygenase 1
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Definition
: A constitutively-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes.
Other names
Synthase, COX-
1 Prostaglandin; Prostaglandin Synthase, COX-
1; Prostaglandin H Synthase 1; Cyclo Oxygenase I; COX 1 Prostaglandin Synthase; Cyclooxygenase-
1; Cyclo-
Oxygenase I; COX-
1 Prostaglandin Synthase; Prostaglandin H Synthase-
1
Substance
CAS Registry & name
Categories
Source
Drugs
*
3-
methoxy-
1,5-
bis(4-
methoxyphenyl)-
1H-
1,2,4-
triazole
0
*Triazoles
Cyclooxygenase Inhibitors
Cyclooxygenase 1.
Biochem Pharmacol 2011 Oct 1;82(7):746-54
ethyl 4-
(benzyloxy)-
3-
((3-
(4-
methoxytetrahydro-
2H-
pyran-
4-
yl)phenyl)methylsulfonamido)benzoate
0
*Benzoates
*Sulfonamides
Lipoxygenase Inhibitors
Cyclooxygenase Inhibitors
Cyclooxygenase 1
Cyclooxygenase 2 Inhibitors.
Bioorg Med Chem 2011 Mar 15;19(6):2074-83
N-
(5-
amino-
2-
pyridinyl)-
4-
trifluoromethylbenzamide
0
*Aminopyridines
*Benzamides
Cyclooxygenase 1.
J Med Chem 2008 Apr 24;51(8):2400-11
2-
(4-
aminophenyl)-
3-
(3,5-
dihydroxylphenyl)propenoic acid
0
*Aniline Compounds
*Caffeic Acids
Arachidonate 5-Lipoxygenase/antagonists & inhibitors
Cyclooxygenase 1
Cyclooxygenase 2.
Basic Clin Pharmacol Toxicol 2009 Nov;105(5):350-6
Ptgs1 protein, rat
EC 1.14.99.1
*Membrane Proteins
*Cyclooxygenase 1.
Ptgs1 protein, mouse
EC 1.14.99.1
*Membrane Proteins
*Cyclooxygenase 1.
PTGS1 protein, human
EC 1.14.99.1
*Cyclooxygenase 1.
mofezolac
78967-07-4
*Isoxazoles
Cyclooxygenase 1.
Pharma Action
Cyclooxygenase Inhibitors
J Chromatogr 1987;422:227