encyclopedia of medical concepts
ψ 
ψ 
ψ 

Receptor, Fibroblast Growth Factor, Type 2

More information in Books or onNLM PubMed
Definition: A fibroblast growth factor receptor that is found in two isoforms. One receptor isoform is found in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform of fibroblast growth factor receptor 2 is found mainly in EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME).     
See Also Acrocephalosyndactylia; Craniofacial Dysostosis 		Other names Bek Related Fibroblast Growth Factor Receptor 1; Receptor, Fibroblast Growth Factor 2c; Receptor, Fibroblast Growth Factor 2b; Fibroblast Growth Factor Receptors 2b; Fibroblast Growth Factor Receptors 2; Fibroblast Growth Factor Receptor 2c; Fibroblast Growth Factor Receptor 2b; FGFR2c; FGFR2 Protein; Bek-Related Fibroblast Growth Factor-Receptor-1; Bek Fgf Receptor Kinase; BEK Protein Tyrosine Kinase; BEK Fibroblast Growth Factor Receptor Kinase; BEK Fibroblast Growth Factor Receptor; Fibroblast Growth Factor Receptor 2; FGFR2b
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
msFGFR2 protein  0   *Peptide Fragments *Recombinant Proteins *Receptor, Fibroblast Growth Factor, Type 2 Receptors, Fibroblast Growth Factor/antagonists & inhibitors. Mol Cancer Ther. 2011 Sep;10(9):1656-66.
fgfr2 protein, zebrafish  EC 2.7.1.112   *Zebrafish Proteins *Receptor, Fibroblast Growth Factor, Type 2.
Fgfr2 protein, Xenopus  EC 2.7.1.112   *Xenopus Proteins *Receptor, Fibroblast Growth Factor, Type 2.
Fgfr2 protein, rat  EC 2.7.1.112   *Receptor, Fibroblast Growth Factor, Type 2.
Fgfr2 protein, mouse  EC 2.7.1.112   *Receptor, Fibroblast Growth Factor, Type 2.
FGFR2 protein, human  EC 2.7.1.112   *Receptor, Fibroblast Growth Factor, Type 2.
keratinocyte growth factor receptor  EC 2.7.1.-   *Receptor, Fibroblast Growth Factor, Type 2 Fibroblast Growth Factors Keratinocytes. J Biol Chem 1990;265(22):12767

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy