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Farnesyltranstransferase

More information in Books or onNLM PubMed
Definition: An enzyme that catalyzes the synthesis of geranylgeranyl diphosphate from trans, trans-farnesyl diphosphate and isopentenyl diphosphate.      Other names Synthase, Geranylgeranyl-Diphosphate; Synthase, GGPP; Synthase, GGDP; Pyrophosphatase, Geranylgeranyl; Geranylgeranyl Diphosphate Synthase; Farnesyl Diphosphate Geranylgeranyl Diphosphate Sy; Geranylgeranyl-Diphosphate Synthase; Geranylgeranyl Pyrophosphatase; GGPP Synthase; GGDP Synthase; Farnesyltransferase; Farnesyl Diphosphate-Geranylgeranyl Diphosphate Sy
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
CH 4512600  0   *Benzofurans *Imidazoles Farnesyltranstransferase/antagonists & inhibitors. Int J Oncol 2008 Jan;32(1):153-9
PB-93 compound  0   *Quinolines *Sulfonamides Farnesyltranstransferase/antagonists & inhibitors. Antimicrob Agents Chemother 2007 Oct;51(10):3659-71
Cpp1 protein, S pombe  EC 2.5.1.29   *Schizosaccharomyces pombe Proteins *Farnesyltranstransferase. J Biol Chem 2000 Jan 7;275(1):429-38
moverastin A  0   *Benzaldehydes *Cyclohexanones Farnesyltranstransferase/antagonists & inhibitors. Chem Biol 2005 Dec;12(12):1337-47
Ggps1 protein, mouse  0   *Multienzyme Complexes *Farnesyltranstransferase.
GGPS1 protein, human  EC 2.5.1.29   *Dimethylallyltranstransferase *Geranyltranstransferase *Farnesyltranstransferase.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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