encyclopedia of medical concepts
ψ
Farnesyltranstransferase
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Definition
: An enzyme that catalyzes the synthesis of geranylgeranyl diphosphate from trans, trans-farnesyl diphosphate and isopentenyl diphosphate.
Other names
Synthase, Geranylgeranyl-
Diphosphate; Synthase, GGPP; Synthase, GGDP; Pyrophosphatase, Geranylgeranyl; Geranylgeranyl Diphosphate Synthase; Farnesyl Diphosphate Geranylgeranyl Diphosphate Sy; Geranylgeranyl-
Diphosphate Synthase; Geranylgeranyl Pyrophosphatase; GGPP Synthase; GGDP Synthase; Farnesyltransferase; Farnesyl Diphosphate-
Geranylgeranyl Diphosphate Sy
Substance
CAS Registry & name
Categories
Source
Drugs
*
CH 4512600
0
*Benzofurans
*Imidazoles
Farnesyltranstransferase/antagonists & inhibitors.
Int J Oncol 2008 Jan;32(1):153-9
PB-
93 compound
0
*Quinolines
*Sulfonamides
Farnesyltranstransferase/antagonists & inhibitors.
Antimicrob Agents Chemother 2007 Oct;51(10):3659-71
Cpp1 protein, S pombe
EC 2.5.1.29
*Schizosaccharomyces pombe Proteins
*Farnesyltranstransferase.
J Biol Chem 2000 Jan 7;275(1):429-38
moverastin A
0
*Benzaldehydes
*Cyclohexanones
Farnesyltranstransferase/antagonists & inhibitors.
Chem Biol 2005 Dec;12(12):1337-47
Ggps1 protein, mouse
0
*Multienzyme Complexes
*Farnesyltranstransferase.
GGPS1 protein, human
EC 2.5.1.29
*Dimethylallyltranstransferase
*Geranyltranstransferase
*Farnesyltranstransferase.