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Sesquiterpenes, Guaiane

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Definition: SESQUITERPENES cyclized into two adjoining rings, one being 7-carbons and the other is 5-carbons.     
Examples Thapsigargin 		Other names Guaianolide Sesquiterpenes; Guaiane Sesquiterpenes; Sesquiterpenes, Guaianolide
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2'-chloroenglerin A  0   *Hydrocarbons, Chlorinated *Sesquiterpenes, Guaiane. J Nat Prod. 2012 Mar 23;75(3):459-63
artemanomalide B  0   *Sesquiterpenes, Guaiane Cyclooxygenase 2 Inhibitors. J Asian Nat Prod Res. 2012 Feb;14(2);111-4
artemanomalide A  0   *Sesquiterpenes, Guaiane Cyclooxygenase 2 Inhibitors. J Asian Nat Prod Res. 2012 Feb;14(2);111-4
2alpha-acetoxy-4alpha,6alpha-dihydroxy-1beta,5alphaH-guai-9(10),11(13)-dien-12,8alpha-olide  0   *Sesquiterpenes, Guaiane Anti-Inflammatory Agents, Non-Steroidal. J Nat Prod. 2011 Sep 23;74(9):1881-7
4beta,10alpha-dihydroxy-5alphaH-guai-1(2),11(13)-dien-12,8alpha-olide  0   *Sesquiterpenes, Guaiane Anti-Inflammatory Agents, Non-Steroidal. J Nat Prod. 2011 Sep 23;74(9):1881-7
8-epigrosheimin  0   *Sesquiterpenes, Guaiane. Org Lett. 2011 Jul 15;13(14):3670-3
9-deoxy-englerin A  0   *Sesquiterpenes, Guaiane. Org Lett. 2011 Apr 15;13(8):2090-3
amberbin B  0   *Sesquiterpenes, Guaiane. Nat Prod Commun. 2010 Dec;5(12):1865-8
amberbin A  0   *Sesquiterpenes, Guaiane. Nat Prod Commun. 2010 Dec;5(12):1865-8
daucusol  0   *Sesquiterpenes, Guaiane. Fitoterapia. 2010 Jul;81(5):443-6
daucuside  0   *Sesquiterpenes, Guaiane. Fitoterapia. 2010 Jul;81(5):443-6
englerin B  0   *Sesquiterpenes, Guaiane. Angew Chem Int Ed Engl. 2010 May 3;49(20):3517-9
torilolone 8-O-beta-D-glucopyranoside  0   *Glucosides *Sesquiterpenes, Guaiane. Pharmazie. 2010 Jan;65(1):69-71
13-nor-pseudoguaianolide  0   *Sesquiterpenes, Guaiane. Org Biomol Chem. 2009 Aug 21;7(16):3230-5
ainsliatrimer B  0   *Sesquiterpenes, Guaiane. Org Lett. 2008 Dec 18;10(24):5517-20
ainsliatrimer A  0   *Sesquiterpenes, Guaiane. Org Lett. 2008 Dec 18;10(24):5517-20
2'-O-E-caffeoyl-8alpha-hydroxy-11alpha,13-dihydro-3beta-O-beta-D-glucozaluzanin C  0   *Glucosides *Sesquiterpenes, Guaiane. Chem Pharm Bull (Tokyo) 2009 Jun;57(6):597-9
8-acetoxy-4,10-dihydroxy-2,11(13)-guaiadiene-12,6-olide  0   *Sesquiterpenes, Guaiane. Fitoterapia 2009 Jan;80(1):54-6
englerin A  0   *Sesquiterpenes, Guaiane. Org Lett 2009 Jan 1;11(1):57-60
sulfocostunolide B  0   *Sesquiterpenes, Guaiane. Chem Pharm Bull (Tokyo) 2008 Jun;56(6):864-5
sulfocostunolide A  0   *Sesquiterpenes, Guaiane. Chem Pharm Bull (Tokyo) 2008 Jun;56(6):864-5
8alpha-O-(3'-hydroxy-3'-methylbutyryl)desacylcynaropicrin  0   *Sesquiterpenes, Guaiane. J Nat Prod 2008 Apr;71(4):678-83
8alpha-O-(2',3'-dihydroxyisobutyryl)11beta,13-dihydrodesacylcynaropicrin  0   *Sesquiterpenes, Guaiane. J Nat Prod 2008 Apr;71(4):678-83
3beta,8alpha-dihydroxy-13-methoxyl-4(14),10(15)-dien-(1alphaH,5alphaH,6beta H,11betaH)-12,6-olide  0   *Sesquiterpenes, Guaiane Stereoisomerism. Nat Prod Res 2007 Mar;21(3):221-6
chinensiolide E  0   *Sesquiterpenes, Guaiane. J Nat Prod 2006 Oct;69(10):1425-8
chinensiolide D  0   *Sesquiterpenes, Guaiane. J Nat Prod 2006 Oct;69(10):1425-8
7,10-epoxy-hedyosminolide  0   *Sesquiterpenes, Guaiane. Fitoterapia. 2005 Dec;76(7-8):620-4
leucomisin  0   *Sesquiterpenes, Guaiane. Eksp Klin Farmakol. 2005 Mar-Apr;68(2):44-6
3alpha,8alpha-dihydroxy-1alphaH,5alphaH,6betaH,7alphaH, 11betaH-guai-4(15),10(14)-dien-6,12-olide 8-O-(2-hydroxy)acrylate  0   *Sesquiterpenes, Guaiane. J Nat Prod 2005 May;68(5):762-5
3alpha,8alpha-dihydroxy-1alphaH,5alphaH,6betaH,7alphaH,11betaH-guai-4(15),10(14)-dien-6,12-olide 8-O-2-hydroxymethylacrylate  0   *Sesquiterpenes, Guaiane. J Nat Prod 2005 May;68(5):762-5
guaia-1(10),11-diene  0   *Sesquiterpenes, Guaiane. Phytochemistry. 2005 Mar;66(6):707-13
absinthin  0   *Sesquiterpenes, Guaiane. J Am Chem Soc 2005 Jan 12;127(1):18-9
8-hydroxyguaiene  0   *Sesquiterpenes, Guaiane. J Nat Prod 2005 Jan;68(1):7-10
8-angeloxy-2,4,10-trihydroxy-6-H,7- H, 11-,H-1(5)-guaien-12,6-olide  0   *Sesquiterpenes, Guaiane. Phytochemistry 2001 Dec;58(8):1189-94
guaiane  0   *Sesquiterpenes, Guaiane. J Nat Prod 2000 Dec;63(12):1626-9
zedolactone A  0   *Sesquiterpenes, Guaiane 4-Butyrolactone/*analogs & derivatives. J Org Chem 2000 Oct 6;65(20):6703-7
buchariol  0 4,10-epoxy-6alpha-hydroxyguaiane  *Sesquiterpenes, Guaiane. Phytochemistry 1999 Dec;52(7):1319-22
torilin  0   Sesquiterpenes, Guaiane. Planta Med 1998 May;64(4):332-4
nortrilobolide  136051-63-3 2-Butenoic acid, 2-methyl-, 6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-2-oxo-4-(1-oxobutoxy)azuleno(4,5-b)furan-8-yl ester, (3S-(3alpha,3abeta,4alpha,6beta,6abeta,8alpha(Z),9balpha))  *Sesquiterpenes, Guaiane *Azulenes Apiaceae Histamine Release. Planta Med 1991;57(2):196
guaiene  88-84-6   *Sesquiterpenes, Guaiane *Azulenes Oils, Volatile. Food Cosmet Toxicol 1979;17(4):371; Yakugaku Zasshi 99(2):209;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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