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Histamine Release

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Definition: The secretion of histamine from mast cell and basophil granules by exocytosis. This can be initiated by a number of factors, all of which involve binding of IgE, cross-linked by antigen, to the mast cell or basophil's Fc receptors. Once released, histamine binds to a number of different target cell receptors and exerts a wide variety of effects.     
See Also p-Methoxy-N-methylphenethylamine 		Other names Histamine Liberation; Histamine Releases; Histamine Liberations
 
SubstanceCAS Registry & nameCategoriesSource
aegeline  0   *Amides Histamine Release/drug effects. Pak J Pharm Sci. 2011 Jul;24(3):359-67
corchoionoside C  0   *Glucosides Histamine Release/antagonists & inhibitors. Chem Pharm Bull (Tokyo) 1997 Mar;45(3):464-9
corchoionoside B  0   *Glucosides Histamine Release/antagonists & inhibitors. Chem Pharm Bull (Tokyo) 1997 Mar;45(3):464-9
corchoionoside A  0   *Glucosides Histamine Release/antagonists & inhibitors. Chem Pharm Bull (Tokyo) 1997 Mar;45(3):464-9
histamine-releasing peptide  123496-28-6   *Oligopeptides Histamine Release. Peptides 1993 Mar-Apr;14(2):117-23
xestobergsterol B  141272-44-8   *Cholestanones Histamine Release. Experientia 1993 Feb 15;49(2):145-9
xestobergsterol A  141272-45-9   *Cholestanones Histamine Release. Experientia 1993 Feb 15;49(2):145-9
nortrilobolide  136051-63-3 2-Butenoic acid, 2-methyl-, 6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-2-oxo-4-(1-oxobutoxy)azuleno(4,5-b)furan-8-yl ester, (3S-(3alpha,3abeta,4alpha,6beta,6abeta,8alpha(Z),9balpha))  *Sesquiterpenes, Guaiane *Azulenes Apiaceae Histamine Release. Planta Med 1991;57(2):196
geigerin  436-45-3   *Sesquiterpenes Histamine Release Plant Extracts. Biochem Pharmacol 1987;36(15):2461
vermeerin  16983-23-6   *Sesquiterpenes Histamine Release Plant Extracts. Biochem Pharmacol 1987;36(15):2461
CI 922  97958-08-2 L-Arginine, compd. with 3,7-dimethoxy-4-phenyl-N-1H-tetrazol-5-yl-4H-furo(3,2-b)indole-2-carboxamide  *Indoles *Tetrazoles Histamine Release/drug effects. Int Arch Allergy Appl Immunol 1985;77(1-2):222
otoline  50643-04-4   *Polymers Histamine Release/drug effects. Farmakol Toksikol 36(5):614;1973
mast cell degranulating peptide  32908-73-9   *Peptides Bee Venoms Histamine Release/drug effects. Br J Pharmacol 65(3):395;1979; Hoppe Seyler Z Physiol Chem 358:331;1977; J Physiol 284:160P;1978
beta-corticotropin (1-19)-nonadecapeptide, Ser(1)-Lys(17,18)  47930-61-0 alpha1-19-Corticotropin, 1-D-serine-17-L-lysine-18-L-lysine  Adrenocorticotropic Hormone/*analogs & derivatives Histamine Release/drug effects. Experientia 30(4):399;1974

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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