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Immunoglobulins, Thyroid-Stimulating

More information in Books or onNLM PubMed
Definition: Autoantibodies that bind to the thyroid-stimulating hormone (TSH) receptor (RECEPTORS, THYROTROPIN) on thyroid epithelial cells. The autoantibodies mimic TSH causing an unregulated production of thyroid hormones characteristic of GRAVES DISEASE.  DF: IG THYROID STIMULATING   
Pharmacological Action Immunologic Factors
See Also Graves Disease; Receptors, Thyrotropin
Examples Long-Acting Thyroid Stimulator 		Other names Thyroid Stimulating Immunoglobulins; Thyroid Stimulating Immunoglobulin; Thyroid Stimulating Antibodies; Stimulating Antibody, Thyroid; Immunoglobulin, Thyroid Stimulating; Antibody, Thyroid Stimulating; Thyroid-Stimulating Immunoglobulin; Thyroid Stimulating Antibody; Immunoglobulin, Thyroid-Stimulating; Thyroid-Stimulating Immunoglobulins; Thyroid-Stimulating Antibodies; Antibodies, Thyroid-Stimulating
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
thyroid stimulation-blocking antibody  0   *Immunoglobulins, Thyroid-Stimulating. Thyroid 1999 Feb;9(2):179-82
thyrotropin-binding inhibitory immunoglobulin  0   *Immunoglobulins, Thyroid-Stimulating Receptors, Thyrotropin. Eur Neurol 1995;35(2):99-103

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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