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Receptors, Growth Factor

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Definition: Cell surface receptors that bind growth or trophic factors with high affinity, triggering intracellular responses which influence the growth, differentiation, or survival of cells.  GEN; prefer specifics; DF: RECEPT GROWTH FACTOR   
Examples Bone Morphogenetic Protein Receptors; Proto-Oncogene Proteins c-met; Receptors, Colony-Stimulating Factor; Receptor, Epidermal Growth Factor; Receptor, erbB-2; Receptor, erbB-3; Receptors, Fibroblast Growth Factor; Receptors, Nerve Growth Factor; Receptors, Platelet-Derived Growth Factor; Receptors, Somatomedin; Receptors, Transforming Growth Factor beta; Receptors, Vascular Endothelial Growth Factor 		Other names Receptor, Trophic Factor; Growth Factors Receptors; Factor Receptor, Trophic; Trophic Factor Receptor; Receptors, Trophic Factor; Receptors, Growth Factors; Trophic Factor Receptors; Growth Factor Receptors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
VEGF Trap R1R2 protein  0   *Recombinant Fusion Proteins *Receptors, Growth Factor. Endocrinology 2002 Jul;143(7):2797-807
3-(2-(5-bromo-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-4,5,6,7-tetrahydro-1H-indol-3-yl)propionic acid  0   *Indoles *Propionic Acids Receptors, Growth Factor/antagonists & inhibitors Receptor Protein-Tyrosine Kinases/antagonists & inhibitors. J Med Chem 2000 Jul 13;43(14):2655-63
3-(2-(2-oxo-1,2-dihydroindol-3-ylidenemethyl)-4,5,6,7-tetrahydro-1H-indol-3-yl)propionic acid  0   *Indoles *Propionic Acids Receptors, Growth Factor/antagonists & inhibitors Receptor Protein-Tyrosine Kinases/antagonists & inhibitors. J Med Chem 2000 Jul 13;43(14):2655-63
midkine receptors  0   *Membrane Glycoproteins *Receptors, Growth Factor. Biochem Biophys Res Commun 2000 Apr 21;270(3):936-41
proliferin receptor, mouse  0   *Receptors, Growth Factor. Endocrinology 1995 Jan;136(1):283-8
agrin receptor  0   *Receptors, Growth Factor. Trends Neurosci 1993 Feb;16(2):72-6
Xmrk protein, Xiphophorus  EC 2.7.1.-   *Receptor Protein-Tyrosine Kinases *Fish Proteins Proto-Oncogene Proteins Receptors, Growth Factor. Pigment Cell Res 1992;Suppl 2:173-80
neurite outgrowth factor receptor  0   *Receptors, Growth Factor. Neurosci Lett 1992 Jun 8; 140(1):78-80
vasculotropin receptor  0   *Receptors, Growth Factor *Receptors, Cytokine. Biol Cell 1991;73(1):1-6
decorin receptor  0   *Receptors, Growth Factor. J Cell Biol 1991;114(1):45
Ngfr protein, rat  136958-07-1   *Nerve Tissue Proteins *Receptors, Growth Factor. J Biol Chem 1991;266(11):7207
MDGF1 protein, human  0   *Receptors, Growth Factor. J Biol Chem 1990;265(4):1874
erythroid differentiation factor receptor  0   *Receptors, Growth Factor. J Biol Chem 1989;264(17):10309
biotin receptor  0   *Receptors, Growth Factor. Biochem Biophys Res Commun 1987;143(3):913

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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