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Dextran Sulfate

More information in Books or onNLM PubMed
Definition: Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.      Other names Sulfate, Sodium Dextran; Sulfate, Dextran; Sulfate Sodium, Dextran; Dextran Sulfate, Sodium; Dextran Sulfate Sodium; Sodium Dextran Sulfate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Retrogen D  0   *Poly I-C *Dextran Sulfate. AIDS 1989;3(12):858
doxivenil gel  76404-08-5 Dextran, hydrogen sulfate, potassium salt, mixt. with 2,5-dihydroxybenzenesulfonic acid calcium salt (2:1)  *Calcium Dobesilate *Dextran Sulfate Drug Combinations. Praxis 67(39):1440;1978
hydrodextran sulfate  0   Dextran Sulfate/*analogs & derivatives. Folia Pharm Jap 69(6):931;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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