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Tumor Suppressor Protein p53

More information in Books or onNLM PubMed
Definition: Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.      Other names p53 Tumor Suppressor Protein; Phosphoprotein, pp53; pp53 Phosphoprotein; p53 Antigen; TRP53 Protein; TP53 Protein; Oncoprotein p53; Cellular Tumor Antigen p53
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
p53 protein, zebrafish  0   *Tumor Suppressor Protein p53 *Zebrafish Proteins. Exp Hematol. 2012 Mar;40(3):228-237.e5
coiled-coil domain-containing protein 8, human  0   *Carrier Proteins Tumor Suppressor Protein p53. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):18937-42
pifithrin-beta  0   *Heterocyclic Compounds with 4 or More Rings Toluene/*analogs & derivatives Tumor Suppressor Protein p53/antagonists & inhibitors. Life Sci. 2011 Apr 25;88(17-18):774-83
TRIM29 protein, mouse  0   *Transcription Factors Tumor Suppressor Protein p53/antagonists & inhibitors. Mol Cell Biol 2010 Jun;30(12):3004-15
PNC-27  0   *Tumor Suppressor Protein p53 Peptide Fragments. Cancer Chemother Pharmacol. 2010 Jul;66(2):325-31)
PNC-28  0   *Tumor Suppressor Protein p53 Peptide Fragments. Int J Cancer 2006 Oct 1;119(7):1577-85
p53 protein (325-355), decaarginyl  0   *Peptide Fragments *Tumor Suppressor Protein p53. Biochemistry 2006 Jan 31;45(4):1116-27
p53 protein (325-355), human  0   *Peptide Fragments *Tumor Suppressor Protein p53. Biochemistry 2006 Jan 31;45(4):1116-27
p44 protein, mouse  0   *Peptide Fragments *Tumor Suppressor Protein p53. Int J Biochem Cell Biol 2005 May;37(5):913-9
TRIAP1 protein, human  0   *Intracellular Signaling Peptides and Proteins Tumor Suppressor Protein p53. Cancer Res. 2005 Feb 15;65(4):1197-206
TP53 protein, human  0   *Tumor Suppressor Protein p53.
p53 protein, Drosophila  0   *Tumor Suppressor Protein p53 *Drosophila Proteins. Mol Cell Biol 2003 May;23(9):3305-19
p53 peptide 264-272, human  0   *Peptide Fragments *Tumor Suppressor Protein p53. Cancer Immun 2002 Apr 16;2:3
CEP-1 protein, C elegans  0   *Tumor Suppressor Protein p53 *Caenorhabditis elegans Proteins Transcription Factors. Science 2001 Oct 19;294(5542):591-5
TP53I3 protein, human  0   *Proto-Oncogene Proteins *Intracellular Signaling Peptides and Proteins Tumor Suppressor Protein p53. Cancer Lett 2000 Aug 1;156(1):63-72
TOPORS protein, human  EC 6.3.2.-   *Neoplasm Proteins *Nuclear Proteins *Ubiquitin-Protein Ligases DNA Topoisomerases, Type I Tumor Suppressor Protein p53 Zinc Fingers. Gene 1999 Jul 22;235(1-2):93-101; Nucleic Acids Res 1999 Jun 15;27(12):2538-44
Trp63 protein, rat  0   *Tumor Suppressor Protein p53. Oncogene 1997 Sep;15(11):1363-7

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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