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4-Nitroquinoline-1-oxide

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Definition: A potent mutagen and carcinogen. This compound and its metabolite 4-HYDROXYAMINOQUINOLINE-1-OXIDE bind to nucleic acids. It inactivates bacteria but not bacteriophage.  D25-26 qualif   
Pharmacological Action Carcinogens; Mutagens 		Other names 4-Nitroquinoline-N-oxide; 4 Nitroquinoline N oxide; 4 Nitroquinoline 1 oxide
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-nitroquinolone-1-oxide  0   *Quinolones 4-Nitroquinoline-1-oxide. Int J Cancer 1999 Jul 30;82(3):377-84
3-methyl-4-nitroquinoline 1-oxide  14073-00-8   4-Nitroquinoline-1-oxide/*analogs & derivatives. Carcinogenesis 1982;3(12):1463
6-nitroquinoline 1-oxide  13675-92-8   4-Nitroquinoline-1-oxide/*analogs & derivatives. Mutat Res 17(1):127;1972
2-methyl-4-nitroquinoline 1-oxide  4831-62-3   4-Nitroquinoline-1-oxide/*analogs & derivatives. Mutation Res 17(1):127;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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