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Thiobarbiturates

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Definition: Compounds in which one or more of the ketone groups on the pyrimidine ring of barbituric acid are replaced by thione groups.     
Examples Thiamylal; Thiopental
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5-(4-vinylbenzyl)-2-thiobarbituric acid  0   *Thiobarbiturates. Dent Mater J 2003 Sep;22(3):343-58
1,3-dibutyl-2-thiobarbituric acid  0   *Thiobarbiturates Smoking. Br J Biomed Sci 2001;58(2):61-5
bis(1,3-dihexyl-2-thiobarbiturate)trimethineoxonol  0   *Thiobarbiturates. Chem Biol 1997 Apr;4(4):269-77
merocil  143413-72-3   *Thiobarbiturates. Anticancer Drugs 1994 Oct;5(5):557-66
5-(2-thiophene)-2-thiobarbituric acid  120244-32-8   *Thiobarbiturates *Thiophenes. Pharmazie 1988;43(12):877
5,5'-(salicylidene)bis-(2-thiobarbituric acid)  27430-16-6   *Thiobarbiturates. Arch Pharm (Weinheim) 1988;321(2):65
isothiobarbamin  96957-66-3 4(1H)-Pyrimidinone, 2-((2-(diethylamino)ethyl)thio)-6- hydroxy-5-(1-methylethyl)-, monohydrochloride  *Thiobarbiturates. Arkh Anat Gistol Embriol 1986;91(8):47
1,3-diphenyl-2-thiobarbituric acid  35221-12-6 4,6(1H,5H)-Pyrimidinedione, dihydro-1,3-diphenyl-2-thioxo  *Thiobarbiturates. Chem Pharm Bull (Tokyo) 1985;33(12):5380
1,3-diethyl-2-thiobarbituric acid  5217-47-0   *Thiobarbiturates. Thorax 1985;40(5):351
merbarone  97534-21-9 5-Pyrimidinecarboxamide, hexahydro-4,6-dioxo-N-phenyl-2-thioxo  *Thiobarbiturates.
Pharma Action Topoisomerase II Inhibitors 		Biochem Pharmacol 1985;34(11):2047
thiobarbituric acid  504-17-6   *Thiobarbiturates. Anal Biochem 1981;110(2):380
4,5-dimethylaminobenzylidene-2-thiobarbituric acid  27430-15-5 4,6(1H,5H)-Pyrimidinedione, 5-((4-(dimethylamino)phenyl)methylene)dihydro-2-thioxo  *Thiobarbiturates. Chem Pharm Bull (Tokyo) 1980;28(8):2518
bis(1,3-diethylthiobarbiturate)trimethineoxonol  47623-98-3 4,6(1H,5H)-Pyrimidinedione, 5-(3-(1,3-diethylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propenylidene)-1,3-diethyldihydro-2-thioxo  *Thiobarbiturates.
Pharma Action Fluorescent Dyes 		Biochim Biophys Acta 1979;595(1):15
methitural  467-43-6   *Thiobarbiturates.
buthalital  468-65-5 5-allyl-5-isobutyl-2-thiobarbituric acid  *Thiobarbiturates.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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