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Topoisomerase II Inhibitors
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Definition
: Compounds that inhibit the activity of DNA TOPOISOMERASE II.
Other names
Inhibitors, Topoisomerase II; Inhibitors, Topoisomerase 2; DNA Type 2 Topoisomerase Inhibitors; DNA Topoisomerase II Inhibitors; Topoisomerase 2 Inhibitors
Substances having this pharmacologic action:
asulacrine
;
6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno(2,1-c)quinolin-7-one
;
pixantrone
;
4,4'-(1,2-dimethyl-1,2-ethanediyl)bis-2,6-piperazinedione
;
sobuzoxane
;
N-(2'-(dimethylamino)ethyl)acridine-4-carboxamide
;
merbarone
Substance
CAS Registry & name
Categories
Source
Drugs
*
4-
((4'-
benzylpiperdin-
4-
yl)amino)-
4'-
O-
demethylepipodophyllotoxin
0
*Piperidines
Podophyllotoxin/*analogs & derivatives
Topoisomerase II Inhibitors.
Cancer Sci. 2012 Jan;103(1):80-7.
tricitinol B
0
*Benzopyrans
*Heterocyclic Compounds with 4 or More Rings
Topoisomerase II Inhibitors.
J Med Chem. 2011 Aug 25;54(16):5796-810.