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Protoporphyrins

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Definition: Porphyrins with four methyl, two vinyl, and two propionic acid side chains attached to the pyrrole rings. Protoporphyrin IX occurs in hemoglobin, myoglobin, and most of the cytochromes.  porphyrins   
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
deuxemether  0   *Deuteroporphyrins *Protoporphyrins. J Photochem Photobiol B 2008 Mar 28;90(3):179-86
protoporphyrin IX-cyclic(arginyl-glycyl-aspartyl-phenylalanyl-lysyl) conjugate  0   *Peptides, Cyclic *Protoporphyrins. Photochem Photobiol Sci 2008 Mar;7(3):290-8
Photolon  0   *Povidone *Protoporphyrins. Biomol Eng 2007 Nov;24(5):425-33
mu-oxo dimeric Fe(III)-protoporphyrin IX  0   *Protoporphyrins. Biochem J 2004 May 1;379(Pt 3):833-40
meso,N-diphenylprotoporphyrin IX  0   *Protoporphyrins. Acta med Okayama 2003 Oct;57(5):249-56
iron protoporphyrin IX  0   *Protoporphyrins Iron. Antioxid Redox Signal 2001 Aug;3(4):685-96
N-vinylprotoporphyrin  0   *Protoporphyrins. Drug Metab Dispos 1996 Aug;24(8):872-8
copper protoporphyrin IX  0   *Protoporphyrins. Proc Natl Acad Sci USA 1995 Mar 14;92(6):1994-7
5-azaprotoporphyrin dimethyl ester  141622-84-6   *Protoporphyrins. J Photochem Photobiol B 1994 May;23(2-3):239-43
PH 1008  126265-02-9   *Protoporphyrins. Lasers Surg Med 1992;12(1)98-103
boron protoporphyrin  0   *Protoporphyrins. Proc Natl Acad Sci USA 1992 Mar 1;89(5):1785-9
lead protoporphyrin  0   *Protoporphyrins Lead. Sci Total Environ 1991 Sep;107:91-8
3(2),3(2),8(2),8(2)-tetrafluoroprotoporphyrin dimethyl ester  123279-53-8   *Protoporphyrins. Chem Pharm Bull (Tokyo) 1990;38(8):2175
8(2),8(2)-difluoroprotoporphyrin dimethyl ester  123279-54-9   *Protoporphyrins. Chem Pharm Bull (Tokyo) 1990;38(8):2175
3(2),3(2)-difluoroprotoporphyrin dimethyl ester  123386-99-2   *Protoporphyrins. Chem Pharm Bull (Tokyo) 1990;38(8):2175
protoporphyrin dimethyl ester hematoporphyrin ether  121806-85-7   *Hematoporphyrins *Protoporphyrins. Biol Chem Hoppe Seyler 1989;370(4):337
nickel(II) protoporphyrin IX  15415-30-2   *Protoporphyrins Nickel. J Mol Biol 1986;192(2):323
magnesium monovinylprotoporphyrin  98606-14-5   *Protoporphyrins. Anal Biochem 1985;149(1):43
acrylochlorin  89759-83-1 21H,23H-Porphine-2,3-dicarboxylic acid, 13-(2-carboxyethenyl)-17-(2-carboxyethyl)-7,8-dihydro-7,8-bis(hydroxymethyl)-7,8,12,18-tetramethyl  *Protoporphyrins. J Biol Chem 1984;259(24):15089
dimethyl protoporphyrin IX  5522-66-7   *Protoporphyrins. Arch Biochem Biophys 1984;230(2):466
nitrosyl(protoporphyrin IX dimethyl ester)iron II  74936-44-0 Iron(1+), (dimethyl 7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(2-)-N21,N22,N23,N24)nitrosyl-, (SP-5-13)  *Protoporphyrins. Arch Biochem Biophys 1984;229(1):126
magnesium protoporphyrin  14947-11-6   *Protoporphyrins. J Inorg Biochem 1983;19(3):189
manganese protoporphyrin  21393-64-6   *Protoporphyrins. J Cell Physiol 1983;116(2):135
chromium protoporphyrin IX  84640-43-7 Chromate(1-), (7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N21,N22,N23,N24)-, hydrogen, (SP-4-2)  *Protoporphyrins. J Exp Med 1982;156(6):1878
N-methylprotoporphyrin dimethyl ester  75675-52-4   *Protoporphyrins Ferrochelatase/antagonists & inhibitors. Biochem J 1982;208(2):479
protoporphyrin IX monomethyl ester  16053-68-2   *Protoporphyrins. Biofizika 1981;26(6):1102
tin protoporphyrin IX  14325-05-4 Stannate(2-), (7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N21,N22,N23,N24)-, dihydrogen, (SP-4-2)  *Metalloporphyrins *Protoporphyrins Heme Oxygenase (Decyclizing)/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors
Proc Natl Acad Sci 1981;78(1):6466
N-phenylprotoporphyrin IX  80367-89-1 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-21-phenyl  *Protoporphyrins. Proc Natl Acad Sci USA 1981;78(9):5508
N-ethylprotoporphyrin IX  80127-70-4 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-21(or 23)-ethyl-3,8,13,17-tetramethyl-, dimethyl ester  *Protoporphyrins. J Biol Chem 1981;256(13):6708
N-(2-hydroxyethyl)protoporphyrin IX  0   *Protoporphyrins. J Biol Chem 1981;256(9):4395
N-methylprotoporphyrin IX  79236-56-9 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17,23-pentamethyl  *Protoporphyrins. Biochem Biophys Res Commun 1980;97(4):1436
protoporphyrin IX  553-12-8   *Protoporphyrins.
Pharma Action Photosensitizing Agents
Int J Biochem 1980;12(5-6):681
2,4-diformylprotoporphyrin IX  0   *Protoporphyrins. Biochemistry 19(2):379;1980
zinc protoporphyrin  15442-64-5 (SP-4-2)-dihydrogen (7,12-diethenyl-3,8,13,17- tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)- N(21),N(22),N(23),N(24))zincate(2-)  *Protoporphyrins Heme Oxygenase (Decyclizing)/antagonists & inhibitors Metalloporphyrins.
Pharma Action Enzyme Inhibitors
J Occup Med 20(6):391;1978
protoporphyrinogen  7412-77-3 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-5,10,15,20,22,24-hexahydro-3,8,13,17-tetramethyl  *Protoporphyrins. Arch Biochem Biophys 1979;197(2):396; Biochem Biophys Res Comm 78(1):429;1977; N Engl J Med 1980;302(14):765; Protein Nucleic Acid Enzyme (Tokyo) 20(12):1079;1975
cobaltiprotoporphyrin  14325-03-2   *Protoporphyrins. Yonago Acta Med 17(1):25;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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