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Hematoporphyrins

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Definition: Iron-free derivatives of heme with 4 methyl groups, 2 hydroxyethyl groups and 2 propionic acid groups attached to the pyrrole rings. Some of these PHOTOSENSITIZING AGENTS are used in the PHOTOTHERAPY of malignant NEOPLASMS.     
Pharmacological Action Photosensitizing Agents
Examples Hematoporphyrin Derivative 		Other names Hemedonin; Hematoporphyrin; Haematoporphyrin IX
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
MPA79  0   *Hematoporphyrins. Clin Cancer Res 2008 Oct 15;14(20):6564-73
hematoporphyrin monomethyl ether  0   *Hematoporphyrins. Cancer Lett 2004 Dec 8;216(1):43-54
hematoporphyrin diethyl ether  0   *Hematoporphyrins. J Photochem Photobiol B 1999 Sep-Oct;52(1-3):35-42
copper(II)-hematoporphyrin  0   *Hematoporphyrins *Metalloporphyrins. Photochem Photobiol 1999 Jun;69(6):708-12
tetramethyl hematoporphyrin  0   *Hematoporphyrins. Urol Res 1995;23(3):151-6
hematoporphyrin IX di-N-propyletherdiethanolamide  0   *Hematoporphyrins. Biophys Chem 1995 Apr;54(2):165-74
haematoporphyrin-transferrin conjugate  0   *Hematoporphyrins *Transferrin. J Photochem Photobiol B 1994 Oct;26(1):45-56
haematoporphyrin-bovine serum albumin conjugate  0   *Hematoporphyrins *Serum Albumin, Bovine. J Photochem Photobiol B 1994 Oct;26(1):45-56
photosan III  136219-06-2   *Hematoporphyrins Photosensitizing Agents. J Photochem Photobiol B 1991;10(1-2):111
hematoporphyrin dipentyl ether  109351-24-8   *Hematoporphyrins. Int J Biochem 1990;22(10):1127
hematoporphyrin HP-5  0   *Hematoporphyrins. J Photochem Photobiol B 1990;6(1-2):175
manganese (III) hematoporphyrin  69997-72-4 Manganate(1-), (7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-21H-23H-porphine-2,18-dipropanoato(2-)-N21,N22,N23,N24)-, hydrogen, (SP-4-2)  *Hematoporphyrins *Metalloporphyrins Manganese. Invest Radiol 1990;25(7):765
protoporphyrin dimethyl ester hematoporphyrin ether  121806-85-7   *Hematoporphyrins *Protoporphyrins. Biol Chem Hoppe Seyler 1989;370(4):337
hematoporphyrin dihexyl ether  111922-13-5   *Hematoporphyrins. Int J Biochem 1988;20(10):1139
hematoporphyrin dicyclohexanyl ether  119052-80-1   *Hematoporphyrins. Int J Biochem 1988;20(10):1139
hematoporphyrin diphenyl ether  119052-81-2   *Hematoporphyrins. Int J Biochem 1988;20(10):1139
bis-1-(deuteroporphyrin-2-yl)ethyl ether tetramethyl ester  116522-71-5   *Hematoporphyrins. Photochem Photobiol 1988;47(6):769
marycin  111775-32-7 Marycin  *Hematoporphyrins. Eur J Cancer Clin Oncol 1987;23(9):1289
photocarcinorin  103939-18-0   *Hematoporphyrins. Chung Kuo Yao Li Hsueh Pao 1986;7(4):346
hematoheme  19584-91-9   *Hematoporphyrins. Anal Biochem 1987;161(2):323
hematoporphyrin D-sepharose  0   *Hematoporphyrins Sepharose/*analogs & derivatives. Photochem Photobiol 1987;45(1):93
hematoporphyrin-sepharose  124399-49-1   *Hematoporphyrins Sepharose/*analogs & derivatives. Methods Enzymol 1986;123:324
hematobiliverdin  83504-29-4   *Hematoporphyrins Biliverdine/*analogs & derivatives. Eur J Biochem 1986;156(1):179
hematohemin IX  15632-20-9   *Hematoporphyrins Hemin/*analogs & derivatives. Eur J Biochem 1986;156(1):179
2,4-diacetylhematoporphyrin dimethyl ester  75162-60-6   *Hematoporphyrins. Yao Hsueh Hsueh Pao 1985;20(7):545
O,O'-diacetylhematoporphyrin  69423-76-3 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis(1-(acetyloxy)ethyl)-3,8,13,17-tetramethyl  *Hematoporphyrins. Biochem J 1983;214(2):503
hematoporphyrin IX dimethylester  32562-61-1   *Hematoporphyrins. Photochem Photobiol 1983;37(1):99
K.H.3  0   *Hematoporphyrins *Procaine Drug Combinations. Geriatrics 1982;37(4):32
N-methylhematoporphyrin  80603-53-8 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17,21-pentamethyl  *Hematoporphyrins. Int J Appl Radiat Isot 1981;32(12):877
hematodeanol  63958-65-6 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-, compd. with 2-(dimethylamino)ethanol (1:1)  *Deanol *Hematoporphyrins. Arzneim Forsch 27(5):1015;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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