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Nalorphine

More information in Books or onNLM PubMed
Definition: A narcotic antagonist with some agonist properties. It is an antagonist at mu opioid receptors and an agonist at kappa opioid receptors. Given alone it produces a broad spectrum of unpleasant effects and it is considered to be clinically obsolete.     
Pharmacological Action Narcotic Antagonists 		Other names Allylnormorphine; Hydrochloride, Nalorphine; Hydrobromide, Nalorphine; Nalorphine, L-tartrate (1:1); Nalorphine, (14 alpha)-Isomer; Nalorphine Hydrochloride; Nalorphine Hydrobromide; Lethidrone
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-cubylmethylnormorphine  0   Nalorphine/*analogs & derivatives. Bioorg Med Chem 1996 Jan;4(1):73-80
nalorphine-7,8-oxide  97242-25-6   Nalorphine/*analogs & derivatives. Gen Pharmacol 1985;16(6):617
N-methylnalorphine  4121-75-9   Nalorphine/*analogs & derivatives. Int J Tissue React 1985;7(1):61
diallylnormorphinium bromide  69576-07-4 Morphinanium, 7,8-didehydro-4,5-epoxy-3,6-dihydroxy-17,17-di-2-propenyl-, bromide, (5alpha,6alpha)  Nalorphine/*analogs & derivatives. Can J Physiol Pharmacol 57(1):98;1979; Eur J Pharmacol 1979;59(2-3):151; Psychopharmacologia 46(2):133;1976
vendal neu  78891-88-0 Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5alpha,6alpha)-, (5alpha,6alpha)-, di-3-pyridinecarboxylate (ester), hydrochloride, mixt. with (5alpha,6alpha)-7,8-didehydro-4,5-epoxy-17-(2-propenyl)morphinan-3,6-diol di-3-pyridinecarboxylate (est  *Morphine Derivatives Drug Combinations Nalorphine/*analogs & derivatives. Wien Med Wochenschr 124(40):587;1974
nalorphine dinicotinate  3194-25-0   Nalorphine/*analogs & derivatives. Wien Med Wochenschr 124(40):587;1974

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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