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Mitolactol

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Definition: Alkylating antineoplastic toxic to bone marrow; used in breast cancer, also in combination with other drugs.     
Pharmacological Action Antineoplastic Agents, Alkylating 		Other names Dibromodulcitol; NSC104800; NSC 104800; NSC-104800
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TPDCV protocol  0   *Antineoplastic Combined Chemotherapy Protocols Lomustine Mitolactol Procarbazine Thioguanine Vincristine. Neuro-oncol 2000 Jan;2(1):22-8
DAVTHML regimen  0   *Antineoplastic Combined Chemotherapy Protocols Doxorubicin Fluoxymesterone Methotrexate Mitolactol Tamoxifen Vincristine. Am J Clin Oncol 1998 Feb;21(1):99-104
TPDC-FuHu protocol  0   *Antineoplastic Combined Chemotherapy Protocols Fluorouracil Hydroxyurea Lomustine Mitolactol Procarbazine Thioguanine. J Clin Oncol 1997 Mar;15(3):1063-70
BVMM protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Methotrexate Mitolactol Vincristine. Neoplasma 1996;43(1):51-6
CDPTH regimen  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Fluoxymesterone Mitolactol Prednisone Tamoxifen. Ann Oncol 1992 Nov;3(9):768-70
DMV regimen  0   *Antineoplastic Combined Chemotherapy Protocols Mitolactol Mitoxantrone Vincristine. Am J Clin Oncol 1991;14(1):45
DAVH protocol  0   *Antineoplastic Combined Chemotherapy Protocols Doxorubicin Fluoxymesterone Mitolactol Vincristine. Cancer 1989;64(7):1393
DAVTH protocol  0   *Antineoplastic Combined Chemotherapy Protocols Doxorubicin Fluoxymesterone Mitolactol Tamoxifen Vincristine. J Clin Oncol 1986;4(1):46
DMV protocol  0   *Antineoplastic Combined Chemotherapy Protocols Mitolactol Vinblastine Mitomycin. Eur J Cancer Clin Oncol 1984;20(7):873
ADM protocol  0   *Antineoplastic Combined Chemotherapy Protocols Doxorubicin Mitolactol Mitomycins. Cancer 1984;53(9):1841
CD protocol  0   *Antineoplastic Combined Chemotherapy Protocols Carubicin Mitolactol. Neoplasma 1982;29(6):741
DAT protocol 2  0   *Antineoplastic Combined Chemotherapy Protocols Doxorubicin Mitolactol Tamoxifen. Am J Clin Oncol 1982;5(5):521
1,2-anhydro-6-bromogalactitol  70791-26-3   Mitolactol/*analogs & derivatives. Eur J Cancer Clin Oncol 1982;18(6):573

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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