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Methaqualone

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Definition: A quinazoline derivative with hypnotic and sedative properties. It has been withdrawn from the market in many countries because of problems with abuse. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)     
Pharmacological Action Hypnotics and Sedatives 		Other names Ortonal; Metolquizolone; Hydrochloride, Methaqualone; Wallace Brand of Methaqualone Hydrochloride; Quaalude; Optimil; Methaqualone Hydrochloride
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-bromomethaqualone  0   Methaqualone/*analogs & derivatives. J Lipid Res 1996 Jul;37(7):1468-80
4'-bromo-3'-methylmethaqualone  0   Methaqualone/*analogs & derivatives. Eur J Biochem 1996 Sep 15;240(3):713-20
methaqualone-1-oxide  2385-41-3   Methaqualone/*analogs & derivatives. Pharmazie 1985;40(5):328
4-oxo-3,4-dihydropyrido(2,3-d)pyrimidine  0   Methaqualone/*analogs & derivatives. Pharmazie 1980;34(5-6):253
2'-hydroxymethylmethaqualone glucuronide  53551-53-4 beta-D-Glucopyranosiduronic acid, (2-(2-methyl-4-oxo-3(4H)-quinazolinyl)phenyl)methyl  Methaqualone/*analogs & derivatives. Z Rechtsmed 1980;85(1):41
Kr 100  14133-24-5 pyrido(2,3-d)pyrimidin-4(3H)-one, 2-methyl-3-(2-methylphenyl)  Methaqualone/*analogs & derivatives. Pharmazie 1979;34(11):732
Ba 51-084512  5060-50-4 2-methyl-3-(2'-hydroxymethylphenyl)-4-(3H)-quinazolinone  Methaqualone/*analogs & derivatives. Drug Metab Disposition 2(4):365;1974
nitromethaqualone  340-52-3   *Nitrophenols Methaqualone/*analogs & derivatives. J Forensic Sci 21(3):552;1976; Verh K Acad Geneeskd Belg 1979;41(4):275
isonox  56335-22-9 2-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone mixt. with 2-(2-(2-(4-((4-chlorophenyl)phenyl methyl)-1-piperazinyl)ethoxy)ethoxy)ethanol(Z)- 2-butenedioate (1:2) (salt)  *Methaqualone *Piperazines Drug Combinations. Eur J Pharmacol 8(3-4):227;1975
lonetil M3  1897-96-7   Methaqualone/*analogs & derivatives. Act Nerv Super (Praha) 18(3):198;1976; Eksp Med Morfol 15(2):79;1976
2-methyl-3-(4'-chlorophenyl)-4-oxo-3,4-dihydropyrido- (2.3-D)pyrimidine  54716-26-6   Methaqualone/*analogs & derivatives. Acta Pharm Suec 11(6):644;1974; Pharmazie 30(2):87;1975; Pharmazie 30(5):2901;1975
Mandrax  8076-99-1   *Diphenhydramine *Methaqualone Drug Combinations.
dimethylquinazolone  1769-25-1   Methaqualone/*analogs & derivatives. Brit J Pharmacol 44(4):805;1972

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