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Levallorphan

More information in Books or onNLM PubMed
Definition: An opioid antagonist with properties similar to those of NALOXONE; in addition it also possesses some agonist properties. It should be used cautiously; levallorphan reverses severe opioid-induced respiratory depression but may exacerbate respiratory depression such as that induced by alcohol or other non-opioid central depressants. (From Martindale, The Extra Pharmacopoeia, 30th ed, p683)     
Pharmacological Action Narcotic Antagonists 		Other names Naloxiphan; LorfanDrugs* : LORFAN
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
SB 227122  0   *Pyrroles Levallorphan/*analogs & derivatives. J Pharmacol Exp Ther 2000 Feb;292(2):803-9
N-methyllevallorphan  63868-46-2   Levallorphan/*analogs & derivatives. Neuropeptides 1985;5(4-6):379
dextrallorphan  5822-43-5   *Levallorphan Stereoisomerism. J Pharmacol Exp Ther 1985;232(1):144
N-allyl levallorphan-bromide  63868-47-3   Levallorphan/*analogs & derivatives. J Pharm Pharmacol 1984;36(5):326
(-)-N-allyl-3,6-beta-dihydroxymorphinan  40678-39-5   Levallorphan/*analogs & derivatives. J Med Chem 16(4):352;1973
pethilorfan  8056-47-1   *Levallorphan *Meperidine Drug Combinations.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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