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Leupeptins

More information in Books or onNLM PubMed
Definition: A group of acylated oligopeptides produced by Actinomycetes that function as protease inhibitors. They have been known to inhibit to varying degrees trypsin, plasmin, KALLIKREINS, papain and the cathepsins.  protease inhib   
Pharmacological Action Protease Inhibitors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
CYLA (leupeptin)  0   *Leupeptins Administration, Oral. Brain Res 2008 Oct 21;1236():206-15
carbobenzoxy-leucyl-leucyl-leucine  0   *Leupeptins. Cell 1996 Mar 8;84(5):769-79
acetyl-leucinyl-leucinyl-methional  0   *Leupeptins. Cell 1994 Sep 9;78(5):761-71
carbobenzoxy-leucyl-leucyl-norvalinal  0   *Leupeptins.
Pharma Action Protease Inhibitors 		Cell 1994 Sep 9;78(5):761-71
benzyloxycarbonylleucyl-leucyl-leucine aldehyde  133407-82-6   *Leupeptins.
Pharma Action Antineoplastic Agents ; Cysteine Proteinase Inhibitors 		Biochem Biophys Res Commun 1992 Jan 31;182(2):939-46
acetylleucyl-leucyl-norleucinal  110044-82-1   *Leupeptins Calpain/antagonists & inhibitors NF-kappa B/antagonists & inhibitors.
Pharma Action Cysteine Proteinase Inhibitors 		J Biochem (Tokyo) 1989;106(6):1035
leupeptin  24365-47-7 L-Leucinamide, N-acetyl-L-leucyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)  *Leupeptins Cathepsins/antagonists & inhibitors.
Pharma Action Cysteine Proteinase Inhibitors 		Biochim Biophys Acta 1981;661(2):175
leupeptin acid  24125-28-8 L-Arginine, N2-(N-(N-acetyl-L-leucyl)-L-leucyl)  *Leupeptins. Biochim Biophys Acta 1981;661(2):175

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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