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Isomerases

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Definition: A class of enzymes that catalyze geometric or structural changes within a molecule to form a single product. The reactions do not involve a net change in the concentrations of compounds other than the substrate and the product.(from Dorland, 28th ed) EC 5.  GEN only; see Tree D8 under ISOMERASES & choose the most specific   
Examples cis-trans-Isomerases; DNA Helicases; DNA Topoisomerases; Intramolecular Lyases; Intramolecular Oxidoreductases; Intramolecular Transferases; Racemases and Epimerases
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
D27 isomerase, Oryza sativa  EC 5.-   *Isomerases *Plant Proteins. Science. 2012 Mar 16;335(6074):1348-51
taxifolin isomerase, Eubacterium ramulus  EC 5.-   *Isomerases. J Nat Prod. 2011 Oct 28;74(10):2243-9
HPGDS protein, mouse  EC 5.-   *Isomerases. Neuroscience. 2009 Sep 29;163(1):296-307
APG10 protein, Arabidopsis  EC 5.-   *Isomerases *Arabidopsis Proteins. Plant Cell Physiol 2005 Jul;46(7):1165-72
DTC1 protein, Oryza sativa  EC 5.-   *Isomerases *Plant Proteins. Plant J 2004 Jan;37(1):1-8
premnaspirodiene synthase  EC 5.-   *Isomerases. Arch Biochem Biophys 2003 Jan 15;409(2):385-94
yellow f2 protein, Drosophila  0   *Carboxy-Lyases *Isomerases *Multienzyme Complexes Drosophila Proteins. Biochem J 2002 Nov;368(Pt 1):333-40
yellow f protein, Drosophila  0   *Carboxy-Lyases *Isomerases *Multienzyme Complexes Drosophila Proteins. Biochem J 2002 Nov;368(Pt 1):333-40
nogalonic acid methyl ester cyclase  EC 5.-   *Bacterial Proteins *Isomerases. Antimicrob Agents Chemother 2000 Feb;44(2):396-9
epicubenol synthase  EC 5.-   *Isomerases. Bioorg Med Chem Lett 2000 Jan 17;10(2):105-7
styrene-oxide isomerase  EC 5.3.99.7   *Isomerases. Appl Environ Microbiol 1998 Jun;64(6):2032-43
2-oxo-3-pentynoic acid  0   *Fatty Acids, Unsaturated Isomerases/antagonists & inhibitors. Biochemistry 1997 Dec 16;36(50):15724-32
MeaA protein, Streptomyces collinus  EC 5.4.99.-   *Bacterial Proteins *Isomerases. J Bacteriol 1997 Aug;179(16):5137-64
isobutyryl-CoA mutase, Streptomyces  EC 5.4.99.-   *Bacterial Proteins *Isomerases. J Bacteriol 1997 Aug;179(16):5157-64
thienamycin cyclase  EC 5.-   *Isomerases. Chin J Biotechnol 1996;12(1):1-7
delta-cadinene synthase  EC 5.-   *Isomerases. Arch Biochem Biophys 1995 Dec 20;324(2):255-66
taxa-4(5),11(12)-diene synthase  EC 5.-   *Isomerases. Arch Biochem Biophys 1995 Oct 1;322(2):437-44
aklanonic acid methyl ester cyclase  EC 5.-   *Isomerases. J Bacteriol 1995 Feb;177(3):536-43
abietadiene cyclase  EC 5.-   *Isomerases Diterpenes, Abietane. Arch Biochem Biophys 1994 Aug 15;313(1):139-49
pinene cyclase III  EC 5.-   *Isomerases. Arch Biochem Biophys 1994 Feb 1;308(2):477-87
S-adenosylmethionine - tRNA ribosyltransferase-isomerase  EC 5.   *Isomerases Bacterial Proteins Escherichia coli Proteins. Biochemistry 1993 Aug 3;32(30):7811-7
Mip-like protein, Chlamydia trachomatis  148294-78-4   *Bacterial Proteins Isomerases. Mol Microbiol 1992 Sep;6(17):2539-48
mannopine cyclase  EC 5.-   *Isomerases. J Bacteriol 1992 Apr;174(7):2215-21
patchoulol synthase  EC 5.-   *Isomerases. Arch Biochem Biophys 1990;282(1):58
aristolochene synthase  EC 5.-   *Isomerases. Arch Biochem Biophys 1989;272(1):137
caryophyllene cyclase  EC 5.-   *Isomerases. Arch Biochem Biophys 1988;261(2):346
humulene cyclase  EC 5.-   *Isomerases. Arch Biochem Biophys 1988;261(2):346
peroxisomal-bifunctional enzyme  EC 4.2.1.17   *Enoyl-CoA Hydratase *Isomerases *3-Hydroxyacyl CoA Dehydrogenases Multienzyme Complexes. Proc Natl Acad Sci USA 1986;83(6):1747
pinene cyclase II  EC 5.-   *Isomerases. J Biol Chem 1984;259(2):740
isopropylmalate isomerase  EC 4.2.1.33   *Isomerases. J Bacteriol 1981;148(1):210
squalene epoxidase-cyclase  0 squalene-2,3-oxide lanosterol cyclase  *Isomerases *Oxygenases. Biochim Biophys Acta 487(1):204;1977; FEBS Lett 34(2):238;1973
prostaglandin isomerases  EC 5.-   *Isomerases. Arch Biochem Biophys 168:96;1975
4-oxalocrotonate tautomerase  EC 5.-   *Isomerases. Eur J Biochem 28(3):347;1972; J Bacteriol 124(2):679;1975
2-methylbutyrate racemase  EC 5.-   *Isomerases. Comp Biochem Physiol 45(3B):617;1973
borneol synthetase  EC 5.-   *Isomerases. Arch Biochem Biophys 184:77;1977

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