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Hexamethonium Compounds

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Definition: Compounds containing the hexamethylenebis(trimethylammonium) cation. Members of this group frequently act as antihypertensive agents and selective ganglionic blocking agents.  antihypertensives; DF: HEXAMETHONIUM CPDS   
Pharmacological Action Antihypertensive Agents; Ganglionic Blockers
Examples Hexamethonium 		Other names Compounds, Hexamethonium
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N,N'-(2,3-dihydroxybenzyl)-N,N,N',N'-tetramethyl-1,6-hexanediamine  159662-70-1   *Catechols *Hexamethonium Compounds. J Med Chem 1994 Dec 9;37(25):4417-20
CHIN 3-6  155114-46-8 1,6-Hexanediaminium, N,N'-bis(3-(3,4-dihydro-4-oxo-2-phenyl-1(2H)-quinazolinyl)propyl)-N,N,N',N'-tetramethyl-, dibromide  *Hexamethonium Compounds *Quinazolines. J Pharm Pharmacol 1994 Feb;46(2):108-12
hylan gel  0   *Cellulose *Hexamethonium Compounds *Tantalum *Thrombin Drug Combinations Hyaluronic Acid/*analogs & derivatives Biocompatible Materials Embolization, Therapeutic. J Biomed Mater Res 1991;25(6):699
benzohexonium  971-60-8 N,N,N,N',N',N'- hexamethyl-1,6-hexanediaminium, dibenzenesulfonate  *Hexamethonium Compounds.
Pharma Action Anti-Ulcer Agents ; Ganglionic Blockers 		Klin Khir 8:53;1979; Terapev Arkhiv 49(1):45;1977
hexafluorenium  4844-10-4   *Fluorenes *Hexamethonium Compounds. Anaesthesia 33(7):649;1978; Arch Int Pharmacodyn Ther 225(2):196;1977; Br J Anaesth 47(8):885;1975; Jpn J Anesthesiol 26(5):534;1977; Naunyn Schmiedebergs Arch Pharmacol 293(1):11;1976; Rev Esp Anestesiol Reanim 25(5):426;1978MYLAXEN

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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