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Factor XI
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Definition
: Stable blood coagulation factor involved in the intrinsic pathway. The activated form XIa activates factor IX to IXa. Deficiency of factor XI is often called hemophilia C.
a blood coag factor
See Also
Coagulants
Examples
Factor XIa
Other names
Plasma Thromboplastin Antecedent; Coagulation Factor XI; XI, Coagulation Factor; Thromboplastin Antecedent, Plasma; Factor XI, Coagulation; Antecedent, Plasma Thromboplastin; Blood Coagulation Factor XI
Substance
CAS Registry & name
Categories
Source
Drugs
*
EP 224283
0
*Oligosaccharides
Biotin/*analogs & derivatives
Factor XI/antagonists & inhibitors
Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors.
J Pharmacol Exp Ther 2011 Aug;338(2):412-20
2-
(2-
hydroxybiphenyl-
3-
yl)-
1H-
indole-
5-
carboxamidine
0
*Amidines
*Indoles
Factor XI/antagonists & inhibitors
Urokinase-Type Plasminogen Activator/antagonists & inhibitors.
J Med Chem 2001 Aug 16;44(17):2753-71
2-
(3-
bromo-
2-
hydroxy-
5-
methylphenyl)-
1H-
indole-
5-
carboxamidine
0
*Amidines
*Indoles
Factor XI/antagonists & inhibitors
Urokinase-Type Plasminogen Activator/antagonists & inhibitors.
J Med Chem 2001 Aug 16;44(17):2753-71